| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 13 | 13 | 10 | 0 | 2.57 | .268 | 1.09 | 7.2 | 2.7 | 7.6 | 94.2 | 75 | 27 | 27 | 11 | 28 | 79 | 0 | 0 | 0 | 0 | 11 | 1 | 1 | 3.77 |
| SP | Mathewson, C.Mathewson, Christy # >> | 28 | 1908 | R | 82 | 13 | 13 | 7 | 4 | 4.25 | .308 | 1.28 | 9.8 | 1.7 | 4.1 | 89.0 | 97 | 50 | 42 | 8 | 17 | 41 | 2 | 0 | 0 | 0 | 8 | 5 | 1 | 3.99 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 13 | 13 | 3 | 5 | 5.03 | .321 | 1.40 | 9.1 | 3.5 | 6.8 | 82.1 | 83 | 56 | 46 | 10 | 32 | 62 | 2 | 0 | 0 | 0 | 8 | 2 | 1 | 4.32 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 24 | 0 | 0 | 0 | 1.52 | .184 | 0.68 | 3.1 | 3.1 | 9.0 | 23.2 | 8 | 4 | 4 | 1 | 8 | 23 | 0 | 19 | 3 | 0 | 0 | 0 | 0 | 2.61 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 25 | 0 | 0 | 1 | 2.61 | .244 | 0.97 | 5.5 | 3.2 | 8.1 | 31.0 | 19 | 9 | 9 | 4 | 11 | 28 | 0 | 1 | 3 | 0 | 0 | 0 | 0 | 3.94 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 29 | 0 | 4 | 2 | 3.55 | .293 | 1.24 | 7.4 | 3.8 | 10.9 | 33.0 | 27 | 13 | 13 | 2 | 14 | 40 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.64 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 77 | 22 | 0 | 1 | 1 | 5.01 | .286 | 1.20 | 6.7 | 4.3 | 8.2 | 23.1 | 17 | 13 | 13 | 2 | 11 | 21 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 3.74 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 66 | 17 | 0 | 2 | 0 | 2.37 | .329 | 1.42 | 8.5 | 4.3 | 10.9 | 19.0 | 18 | 8 | 5 | 1 | 9 | 23 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 2.84 |
| SP | Reulbach, E.Reulbach, Ed >> | 23 | 1905 | R | 63 | 6 | 0 | 3 | 0 | 2.45 | .279 | 1.16 | 6.8 | 3.7 | 3.4 | 29.1 | 22 | 9 | 8 | 0 | 12 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.48 |