| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 27 | 27 | 11 | 5 | 3.11 | .281 | 1.17 | 8.0 | 2.6 | 9.1 | 176.2 | 156 | 69 | 61 | 19 | 50 | 177 | 0 | 0 | 0 | 0 | 18 | 1 | 0 | 3.26 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 26 | 26 | 9 | 11 | 5.68 | .336 | 1.49 | 10.7 | 2.8 | 9.2 | 160.0 | 190 | 109 | 101 | 30 | 49 | 164 | 2 | 0 | 0 | 0 | 9 | 4 | 4 | 4.38 |
| SP | Sutton, D.Sutton, Don # >> | 27 | 1972 | R | 82 | 25 | 25 | 8 | 12 | 3.86 | .311 | 1.34 | 8.4 | 3.7 | 5.2 | 186.2 | 173 | 97 | 80 | 18 | 77 | 108 | 7 | 0 | 0 | 2 | 14 | 3 | 4 | 4.39 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 24 | 24 | 6 | 12 | 5.65 | .362 | 1.69 | 10.0 | 5.2 | 8.6 | 129.0 | 144 | 87 | 81 | 19 | 74 | 123 | 0 | 0 | 0 | 0 | 12 | 2 | 2 | 4.78 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 47 | 0 | 0 | 5 | 4.97 | .339 | 1.49 | 9.9 | 3.7 | 7.2 | 41.2 | 45 | 25 | 23 | 7 | 17 | 33 | 0 | 26 | 8 | 0 | 0 | 2 | 1 | 5.00 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 62 | 0 | 3 | 2 | 5.74 | .368 | 1.72 | 9.6 | 5.9 | 8.4 | 47.0 | 50 | 31 | 30 | 10 | 31 | 44 | 0 | 4 | 1 | 0 | 0 | 1 | 2 | 5.94 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 63 | 0 | 1 | 1 | 5.25 | .379 | 1.81 | 8.5 | 7.8 | 8.5 | 36.0 | 34 | 24 | 21 | 2 | 31 | 34 | 0 | 1 | 0 | 0 | 0 | 1 | 4 | 4.50 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 45 | 0 | 7 | 2 | 2.76 | .310 | 1.35 | 8.6 | 3.6 | 11.4 | 42.1 | 40 | 18 | 13 | 6 | 17 | 53 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.55 |