| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 87 | 10 | 10 | 5 | 3 | 3.45 | .287 | 1.17 | 7.7 | 2.8 | 4.5 | 70.1 | 60 | 31 | 27 | 7 | 22 | 35 | 2 | 0 | 0 | 1 | 7 | 3 | 2 | 4.37 |
| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 94 | 10 | 10 | 6 | 4 | 3.25 | .270 | 1.10 | 7.5 | 2.4 | 7.7 | 74.2 | 62 | 28 | 27 | 8 | 20 | 63 | 3 | 0 | 0 | 0 | 6 | 1 | 1 | 3.55 |
| SP | Imanaga, S.Imanaga, Shota >> | 31 | 2025 | L | 53 | 9 | 9 | 2 | 3 | 5.11 | .330 | 1.45 | 10.0 | 3.1 | 5.7 | 44.0 | 49 | 25 | 25 | 5 | 15 | 28 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.30 |
| SP | Wesneski, H.Wesneski, Hayden >> | 24 | 2022 | R | 77 | 9 | 9 | 0 | 1 | 4.09 | .313 | 1.36 | 9.0 | 3.3 | 8.6 | 22.0 | 22 | 11 | 10 | 3 | 8 | 21 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.95 |
| SP | Pfiester, J.Pfiester, Jack >> | 29 | 1907 | L | 59 | 9 | 9 | 2 | 4 | 3.74 | .281 | 1.15 | 7.3 | 3.1 | 3.9 | 53.0 | 43 | 23 | 22 | 5 | 18 | 23 | 0 | 0 | 0 | 0 | 4 | 1 | 1 | 4.43 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 33 | 2021 | R | 100 | 23 | 0 | 3 | 2 | 1.34 | .205 | 0.77 | 3.5 | 3.5 | 8.5 | 33.2 | 13 | 5 | 5 | 0 | 13 | 31 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 2.30 |
| RP | Tepera, R.Tepera, Ryan >> | 33 | 2021 | R | 90 | 21 | 0 | 0 | 0 | 3.21 | .288 | 1.18 | 5.8 | 4.8 | 9.6 | 28.0 | 18 | 12 | 10 | 1 | 15 | 30 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 3.04 |
| RP | Edwards, C.Edwards, Carl >> | 24 | 2016 | R | 94 | 23 | 0 | 2 | 2 | 5.24 | .309 | 1.34 | 5.3 | 7.0 | 10.6 | 22.1 | 13 | 13 | 13 | 3 | 17 | 26 | 0 | 2 | 0 | 0 | 0 | 0 | 6 | 4.73 |
| RP | Hodge, P.Hodge, Porter >> | 23 | 2024 | R | 83 | 13 | 0 | 1 | 1 | 5.87 | .361 | 1.63 | 9.6 | 5.4 | 12.0 | 15.1 | 16 | 11 | 10 | 2 | 9 | 20 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.07 |
| RP | Ramsdell, W.Ramsdell, Willie >> | 36 | 1952 | R | 45 | 12 | 0 | 4 | 0 | 1.85 | .232 | 0.90 | 5.6 | 2.6 | 6.0 | 24.1 | 15 | 6 | 5 | 2 | 7 | 16 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.63 |