| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 31 | 31 | 17 | 10 | 3.52 | .276 | 1.13 | 7.9 | 2.3 | 6.3 | 232.2 | 203 | 93 | 91 | 23 | 60 | 163 | 8 | 0 | 0 | 2 | 18 | 3 | 5 | 3.70 |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 76 | 31 | 31 | 16 | 9 | 3.84 | .288 | 1.18 | 8.1 | 2.5 | 8.5 | 192.1 | 173 | 83 | 82 | 20 | 53 | 182 | 0 | 0 | 0 | 0 | 16 | 7 | 2 | 3.40 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 32 | 32 | 12 | 13 | 4.24 | .324 | 1.39 | 8.4 | 4.1 | 7.5 | 210.0 | 197 | 109 | 99 | 21 | 95 | 174 | 3 | 0 | 0 | 0 | 19 | 10 | 5 | 4.14 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 20 | 3 | 4 | 3 | 4.19 | .327 | 1.44 | 7.7 | 5.3 | 8.8 | 88.0 | 75 | 41 | 41 | 13 | 52 | 86 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.77 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 61 | 0 | 4 | 2 | 2.52 | .283 | 1.15 | 6.2 | 4.4 | 6.5 | 60.2 | 41 | 17 | 17 | 6 | 29 | 43 | 0 | 14 | 4 | 0 | 0 | 2 | 0 | 4.42 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 25 | 0 | 3 | 1 | 5.29 | .312 | 1.36 | 8.4 | 3.9 | 7.9 | 32.1 | 30 | 19 | 19 | 3 | 14 | 28 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.78 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 18 | 0 | 3 | 1 | 1.59 | .203 | 0.76 | 4.2 | 2.6 | 6.4 | 17.0 | 8 | 5 | 3 | 0 | 5 | 12 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 2.47 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 10 | 0 | 0 | 0 | 5.63 | .314 | 1.38 | 10.1 | 2.3 | 7.9 | 8.0 | 9 | 6 | 5 | 1 | 2 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.63 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 14 | 0 | 0 | 0 | 2.16 | .231 | 0.90 | 6.2 | 2.3 | 11.3 | 16.2 | 11 | 4 | 4 | 2 | 4 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.88 |