| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 10 | 10 | 4 | 4 | 3.00 | .253 | 1.01 | 6.9 | 2.3 | 8.5 | 72.0 | 55 | 25 | 24 | 3 | 18 | 68 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | 2.40 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 79 | 10 | 10 | 3 | 6 | 4.85 | .299 | 1.25 | 9.0 | 2.2 | 7.3 | 65.0 | 65 | 35 | 35 | 5 | 16 | 53 | 1 | 0 | 0 | 0 | 4 | 2 | 4 | 3.20 |
| SP | Cicotte, E.Cicotte, Eddie # >> | 33 | 1917 | R | 74 | 9 | 9 | 4 | 4 | 5.43 | .323 | 1.43 | 9.6 | 3.3 | 4.4 | 63.0 | 67 | 38 | 38 | 5 | 23 | 31 | 2 | 0 | 0 | 0 | 3 | 0 | 0 | 4.14 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 27 | 0 | 2 | 1 | 1.07 | .279 | 1.10 | 6.0 | 4.1 | 8.2 | 33.2 | 22 | 5 | 4 | 2 | 15 | 30 | 0 | 4 | 0 | 0 | 0 | 2 | 0 | 3.52 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 87 | 18 | 0 | 0 | 2 | 6.85 | .316 | 1.34 | 9.0 | 3.3 | 7.0 | 22.1 | 22 | 17 | 17 | 3 | 8 | 17 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.45 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 16 | 0 | 2 | 0 | 4.50 | .318 | 1.40 | 9.5 | 3.2 | 7.7 | 20.0 | 21 | 10 | 10 | 1 | 7 | 17 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.00 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 62 | 9 | 0 | 1 | 0 | 3.86 | .340 | 1.54 | 7.4 | 7.4 | 8.2 | 11.2 | 9 | 5 | 5 | 0 | 9 | 10 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.64 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 57 | 4 | 0 | 0 | 0 | 3.38 | .333 | 1.50 | 10.8 | 3.6 | 10.8 | 5.1 | 6 | 2 | 2 | 0 | 2 | 6 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1.80 |