| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 16 | 16 | 10 | 4 | 3.79 | .287 | 1.18 | 7.8 | 2.8 | 8.9 | 121.0 | 105 | 52 | 51 | 7 | 38 | 119 | 6 | 0 | 0 | 0 | 10 | 3 | 2 | 2.80 |
| SP | Steele, E.Steele, Elmer >> | 22 | 1908 | R | 84 | 16 | 16 | 10 | 4 | 3.59 | .289 | 1.19 | 9.1 | 1.6 | 5.4 | 128.0 | 129 | 56 | 51 | 15 | 23 | 77 | 5 | 0 | 0 | 1 | 10 | 4 | 0 | 3.95 |
| SP | Buchholz, C.Buchholz, Clay # >> | 29 | 2013 | R | 70 | 15 | 15 | 7 | 6 | 4.36 | .326 | 1.43 | 8.3 | 4.6 | 6.4 | 105.1 | 97 | 51 | 51 | 5 | 54 | 75 | 3 | 0 | 0 | 0 | 9 | 2 | 4 | 3.79 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 42 | 0 | 2 | 1 | 2.47 | .232 | 0.91 | 7.1 | 1.1 | 9.9 | 58.1 | 46 | 20 | 16 | 6 | 7 | 64 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 2.50 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 29 | 2017 | R | 99 | 28 | 0 | 2 | 2 | 3.31 | .274 | 1.07 | 7.0 | 2.8 | 9.3 | 32.2 | 25 | 13 | 12 | 3 | 10 | 33 | 0 | 6 | 2 | 0 | 0 | 2 | 2 | 3.28 |
| RP | Brasier, R.Brasier, Ryan >> | 30 | 2018 | R | 83 | 13 | 0 | 1 | 0 | 6.30 | .333 | 1.50 | 11.7 | 1.8 | 6.3 | 10.0 | 13 | 7 | 7 | 1 | 2 | 7 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 3.50 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 70 | 3 | 0 | 1 | 0 | 5.40 | .211 | 0.80 | 7.2 | 0.0 | 16.2 | 5.0 | 4 | 3 | 3 | 2 | 0 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.60 |
| RP | O'Brien, B.O'Brien, Buck >> | 29 | 1911 | R | 42 | 2 | 0 | 1 | 0 | 0.00 | .000 | 0.00 | 0.0 | 0.0 | 13.5 | 2.1 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 |
| RP | Strahm, M.Strahm, Matt >> | 30 | 2022 | L | 29 | 17 | 0 | 0 | 0 | 1.89 | .260 | 1.00 | 6.2 | 2.8 | 10.9 | 19.0 | 13 | 4 | 4 | 1 | 6 | 23 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.37 |
| RP | Atchison, S.Atchison, Scott >> | 34 | 2010 | R | 13 | 7 | 0 | 0 | 0 | 8.59 | .413 | 2.11 | 16.1 | 3.9 | 6.4 | 14.2 | 25 | 14 | 14 | 6 | 6 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 8.43 |