| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 89 | 20 | 20 | 7 | 9 | 4.00 | .284 | 1.19 | 8.4 | 2.3 | 8.0 | 139.1 | 130 | 62 | 62 | 16 | 36 | 124 | 6 | 0 | 0 | 0 | 12 | 0 | 2 | 3.49 |
| SP | Greinke, Z.Greinke, Zack >> | 36 | 2019 | R | 69 | 20 | 20 | 5 | 10 | 4.56 | .301 | 1.25 | 8.7 | 2.7 | 5.1 | 132.1 | 127 | 72 | 67 | 15 | 39 | 75 | 1 | 0 | 0 | 1 | 8 | 5 | 1 | 4.34 |
| SP | Kelly, M.Kelly, Merrill >> | 36 | 2025 | R | 63 | 20 | 19 | 11 | 7 | 3.95 | .313 | 1.36 | 8.4 | 3.9 | 6.3 | 114.0 | 106 | 51 | 50 | 11 | 49 | 80 | 0 | 0 | 0 | 0 | 12 | 1 | 0 | 4.17 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 68 | 51 | 0 | 3 | 3 | 3.34 | .294 | 1.25 | 6.0 | 5.2 | 9.1 | 67.1 | 45 | 25 | 25 | 8 | 39 | 68 | 0 | 3 | 4 | 0 | 0 | 0 | 2 | 4.27 |
| RP | Ramirez, N.Ramirez, Noe >> | 31 | 2021 | R | 65 | 44 | 0 | 4 | 1 | 2.51 | .249 | 0.94 | 4.9 | 3.6 | 7.1 | 57.1 | 31 | 17 | 16 | 7 | 23 | 45 | 0 | 7 | 2 | 0 | 0 | 3 | 5 | 4.39 |
| RP | Miller, S.Miller, Shelby >> | 34 | 2025 | R | 50 | 18 | 0 | 1 | 1 | 2.21 | .265 | 1.03 | 5.4 | 4.1 | 7.7 | 20.1 | 12 | 5 | 5 | 2 | 9 | 17 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.10 |
| RP | Crichton, S.Crichton, Stefan >> | 27 | 2019 | R | 42 | 16 | 0 | 0 | 3 | 3.77 | .283 | 1.19 | 7.1 | 3.9 | 9.0 | 14.1 | 11 | 6 | 6 | 2 | 6 | 14 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 4.14 |
| RP | Hernandez, D.Hernandez, David >> | 26 | 2011 | R | 40 | 13 | 0 | 1 | 0 | 1.02 | .243 | 0.96 | 5.3 | 3.7 | 6.9 | 17.2 | 10 | 2 | 2 | 0 | 7 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.71 |
| SP | Godley, Z.Godley, Zack # >> | 27 | 2017 | R | 51 | 14 | 0 | 0 | 2 | 5.80 | .319 | 1.39 | 9.8 | 2.7 | 10.2 | 59.0 | 64 | 41 | 38 | 10 | 18 | 67 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 3.90 |