| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 95 | 27 | 27 | 10 | 11 | 4.81 | .326 | 1.43 | 9.3 | 3.6 | 9.0 | 172.0 | 177 | 97 | 92 | 19 | 69 | 172 | 0 | 0 | 0 | 0 | 12 | 4 | 6 | 3.71 |
| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 67 | 26 | 26 | 7 | 11 | 5.80 | .315 | 1.35 | 9.7 | 2.5 | 8.5 | 170.2 | 183 | 115 | 110 | 33 | 48 | 161 | 3 | 0 | 0 | 0 | 6 | 4 | 1 | 4.55 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 25 | 25 | 11 | 8 | 4.23 | .308 | 1.32 | 8.7 | 3.2 | 4.3 | 161.2 | 156 | 81 | 76 | 17 | 57 | 77 | 0 | 0 | 0 | 0 | 13 | 3 | 4 | 4.53 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 24 | 24 | 6 | 10 | 6.14 | .372 | 1.74 | 10.4 | 5.3 | 4.6 | 132.0 | 152 | 94 | 90 | 17 | 78 | 67 | 0 | 0 | 0 | 0 | 10 | 5 | 0 | 5.55 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 25 | 24 | 5 | 13 | 6.45 | .359 | 1.65 | 11.4 | 3.6 | 4.5 | 149.1 | 188 | 111 | 107 | 18 | 59 | 74 | 4 | 0 | 0 | 0 | 8 | 4 | 7 | 4.85 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 95 | 71 | 0 | 3 | 5 | 3.97 | .313 | 1.37 | 8.4 | 4.0 | 8.0 | 90.2 | 84 | 48 | 40 | 13 | 40 | 80 | 0 | 5 | 4 | 0 | 0 | 0 | 1 | 4.43 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 58 | 53 | 0 | 5 | 6 | 6.00 | .386 | 1.85 | 9.5 | 7.1 | 5.7 | 87.0 | 92 | 61 | 58 | 7 | 69 | 55 | 0 | 6 | 4 | 0 | 0 | 3 | 3 | 5.26 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 52 | 27 | 3 | 5 | 3 | 4.59 | .323 | 1.41 | 9.2 | 3.5 | 6.9 | 51.0 | 52 | 30 | 26 | 7 | 20 | 39 | 1 | 1 | 0 | 0 | 2 | 1 | 0 | 4.49 |