| SP | Koufax, S.Koufax, Sandy # >> | 30 | 1965 | L | 98 | 12 | 12 | 5 | 5 | 4.45 | .299 | 1.26 | 8.4 | 3.0 | 7.4 | 97.0 | 90 | 51 | 48 | 12 | 32 | 80 | 3 | 0 | 0 | 0 | 7 | 2 | 1 | 4.01 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 12 | 12 | 2 | 9 | 5.71 | .319 | 1.39 | 9.3 | 3.2 | 4.0 | 82.0 | 85 | 54 | 52 | 13 | 29 | 36 | 2 | 0 | 0 | 0 | 4 | 1 | 2 | 5.28 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 12 | 12 | 3 | 9 | 5.79 | .329 | 1.43 | 9.9 | 3.1 | 3.7 | 82.1 | 90 | 54 | 53 | 11 | 28 | 34 | 2 | 0 | 0 | 0 | 5 | 3 | 4 | 5.05 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 11 | 11 | 5 | 6 | 3.74 | .324 | 1.42 | 9.4 | 3.4 | 4.9 | 84.1 | 88 | 44 | 35 | 8 | 32 | 46 | 5 | 0 | 0 | 0 | 6 | 1 | 4 | 4.32 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 11 | 11 | 4 | 3 | 4.74 | .358 | 1.66 | 9.3 | 5.8 | 9.1 | 62.2 | 64 | 33 | 33 | 7 | 40 | 63 | 0 | 0 | 0 | 0 | 4 | 1 | 0 | 4.42 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 27 | 0 | 1 | 1 | 1.59 | .261 | 0.99 | 4.6 | 4.4 | 7.0 | 45.1 | 23 | 9 | 8 | 4 | 22 | 35 | 0 | 2 | 0 | 0 | 0 | 3 | 0 | 4.27 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 24 | 0 | 0 | 2 | 4.88 | .294 | 1.25 | 7.1 | 4.1 | 6.4 | 24.0 | 19 | 13 | 13 | 3 | 11 | 17 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 4.58 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 68 | 10 | 0 | 0 | 2 | 5.19 | .316 | 1.33 | 10.1 | 2.1 | 5.8 | 17.1 | 19 | 10 | 10 | 4 | 4 | 11 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 5.65 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 53 | 7 | 0 | 1 | 0 | 4.40 | .317 | 1.40 | 10.3 | 2.6 | 10.3 | 14.1 | 16 | 7 | 7 | 2 | 4 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.43 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 1 | 0 | 0 | 0 | 0.00 | .000 | 0.00 | - | - | - | 0.1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | - |