| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 12 | 12 | 7 | 2 | 3.13 | .294 | 1.22 | 8.0 | 3.0 | 7.1 | 89.0 | 79 | 33 | 31 | 4 | 30 | 70 | 3 | 0 | 0 | 1 | 8 | 2 | 0 | 3.09 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 86 | 11 | 11 | 4 | 3 | 3.05 | .289 | 1.22 | 8.2 | 2.8 | 7.3 | 79.2 | 72 | 32 | 27 | 8 | 25 | 64 | 1 | 0 | 0 | 0 | 9 | 0 | 1 | 3.65 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 11 | 11 | 3 | 3 | 4.94 | .315 | 1.37 | 10.0 | 2.3 | 4.1 | 82.0 | 91 | 46 | 45 | 9 | 21 | 37 | 1 | 0 | 0 | 0 | 4 | 1 | 1 | 4.33 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 11 | 11 | 4 | 4 | 4.56 | .338 | 1.48 | 8.6 | 4.7 | 5.3 | 77.0 | 74 | 44 | 39 | 8 | 40 | 45 | 1 | 0 | 0 | 0 | 5 | 4 | 3 | 4.90 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 29 | 0 | 0 | 2 | 2.89 | .304 | 1.31 | 8.5 | 3.4 | 8.3 | 37.1 | 35 | 12 | 12 | 4 | 14 | 34 | 0 | 2 | 3 | 0 | 0 | 0 | 2 | 3.70 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 22 | 0 | 3 | 1 | 4.38 | .308 | 1.30 | 6.8 | 5.3 | 7.9 | 24.2 | 18 | 13 | 12 | 2 | 14 | 21 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 4.21 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 18 | 0 | 1 | 2 | 2.01 | .247 | 0.99 | 6.1 | 2.9 | 9.4 | 22.1 | 15 | 5 | 5 | 4 | 7 | 23 | 0 | 3 | 1 | 0 | 0 | 0 | 1 | 4.23 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 56 | 1 | 0 | 0 | 0 | 0.00 | .333 | 1.50 | - | - | - | 0.2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 4 | 0 | 2 | 1 | 3.60 | .333 | 1.50 | 9.0 | 4.5 | 7.2 | 10.0 | 10 | 4 | 4 | 0 | 5 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.90 |