| SP | Leonard, D.Leonard, Dutch $ >> | 22 | 1914 | L | 91 | 33 | 33 | 16 | 7 | 3.53 | .287 | 1.18 | 7.2 | 3.5 | 4.5 | 217.0 | 173 | 88 | 85 | 23 | 84 | 108 | 3 | 0 | 0 | 0 | 22 | 5 | 4 | 4.61 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 32 | 32 | 15 | 8 | 3.96 | .284 | 1.17 | 8.7 | 1.9 | 4.3 | 232.0 | 224 | 113 | 102 | 24 | 48 | 111 | 3 | 0 | 0 | 0 | 19 | 4 | 5 | 4.06 |
| SP | Ryan, N.Ryan, Nolan † $$ >> | 44 | 1991 | R | 73 | 31 | 31 | 17 | 7 | 3.88 | .313 | 1.36 | 7.9 | 4.4 | 7.3 | 199.2 | 174 | 90 | 86 | 23 | 97 | 161 | 0 | 0 | 0 | 0 | 15 | 2 | 7 | 4.38 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 87 | 82 | 0 | 7 | 4 | 2.66 | .269 | 1.09 | 7.3 | 2.5 | 7.2 | 101.1 | 82 | 30 | 30 | 4 | 28 | 81 | 0 | 2 | 3 | 0 | 0 | 2 | 0 | 2.80 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 63 | 0 | 7 | 1 | 3.21 | .253 | 0.97 | 6.9 | 1.8 | 8.6 | 73.0 | 56 | 30 | 26 | 10 | 15 | 70 | 0 | 2 | 3 | 0 | 0 | 3 | 0 | 3.60 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 35 | 0 | 1 | 8 | 3.89 | .339 | 1.54 | 10.2 | 3.6 | 7.1 | 37.0 | 42 | 17 | 16 | 5 | 15 | 29 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 4.41 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 67 | 25 | 0 | 3 | 1 | 2.81 | .245 | 0.97 | 6.1 | 2.9 | 5.8 | 25.2 | 17 | 8 | 8 | 4 | 8 | 16 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.76 |
| CL | Chapman, A.Chapman, Aroldis † >> | 37 | 2025 | L | 96 | 67 | 0 | 1 | 1 | 2.39 | .252 | 0.94 | 5.3 | 3.3 | 7.8 | 60.1 | 35 | 16 | 16 | 4 | 22 | 52 | 0 | 57 | 1 | 0 | 0 | 4 | 8 | 3.43 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 16 | 1 | 2 | 4 | 6.34 | .355 | 1.62 | 10.5 | 4.2 | 5.0 | 65.1 | 76 | 51 | 46 | 9 | 30 | 36 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 5.17 |