| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 12 | 12 | 7 | 1 | 4.19 | .295 | 1.25 | 8.6 | 2.8 | 10.2 | 68.2 | 65 | 33 | 32 | 12 | 21 | 77 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | 3.96 |
| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 91 | 12 | 12 | 4 | 4 | 6.22 | .350 | 1.60 | 11.7 | 2.7 | 8.5 | 59.1 | 77 | 41 | 41 | 11 | 18 | 56 | 0 | 0 | 0 | 0 | 3 | 1 | 1 | 4.49 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 12 | 12 | 2 | 5 | 6.64 | .376 | 1.79 | 12.1 | 4.1 | 4.4 | 63.2 | 85 | 50 | 47 | 20 | 29 | 31 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 7.57 |
| CL | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 31 | 0 | 1 | 1 | 1.20 | .250 | 0.93 | 5.1 | 3.3 | 11.4 | 30.0 | 17 | 5 | 4 | 1 | 11 | 38 | 0 | 16 | 0 | 0 | 0 | 2 | 1 | 2.20 |
| SU | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 32 | 0 | 3 | 1 | 2.74 | .273 | 1.10 | 6.4 | 3.6 | 6.4 | 42.2 | 30 | 13 | 13 | 2 | 17 | 30 | 0 | 4 | 0 | 0 | 0 | 1 | 1 | 3.48 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 30 | 0 | 1 | 1 | 3.34 | .300 | 1.29 | 8.0 | 3.6 | 9.5 | 35.0 | 31 | 13 | 13 | 2 | 14 | 37 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 2.83 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 37 | 0 | 2 | 1 | 4.50 | .282 | 1.15 | 6.6 | 3.7 | 10.6 | 34.0 | 25 | 17 | 17 | 2 | 14 | 40 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 2.74 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 26 | 0 | 2 | 1 | 3.96 | .319 | 1.38 | 10.3 | 2.3 | 7.8 | 36.1 | 41 | 16 | 16 | 4 | 9 | 31 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 3.56 |