| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 15 | 15 | 9 | 4 | 3.58 | .315 | 1.35 | 7.7 | 4.6 | 3.3 | 100.2 | 85 | 42 | 40 | 6 | 51 | 37 | 0 | 0 | 0 | 0 | 8 | 3 | 1 | 4.66 |
| SP | Coveleski, S.Coveleski, Stan # >> | 28 | 1917 | R | 62 | 15 | 15 | 8 | 3 | 4.30 | .307 | 1.29 | 8.1 | 3.5 | 4.4 | 92.0 | 83 | 45 | 44 | 7 | 36 | 45 | 0 | 0 | 0 | 0 | 9 | 3 | 1 | 4.28 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 51 | 15 | 10 | 5 | 3 | 3.84 | .292 | 1.20 | 8.3 | 2.6 | 4.7 | 91.1 | 84 | 42 | 39 | 13 | 26 | 48 | 4 | 0 | 0 | 0 | 4 | 3 | 0 | 4.76 |
| CL | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 36 | 0 | 1 | 5 | 3.51 | .281 | 1.17 | 6.5 | 4.1 | 8.2 | 33.1 | 24 | 16 | 13 | 5 | 15 | 30 | 0 | 25 | 3 | 0 | 0 | 0 | 0 | 4.52 |
| SU | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 36 | 0 | 0 | 0 | 3.16 | .270 | 1.08 | 6.3 | 3.4 | 7.8 | 37.0 | 26 | 13 | 13 | 3 | 14 | 32 | 0 | 1 | 3 | 0 | 0 | 1 | 2 | 3.54 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 37 | 26 | 0 | 1 | 0 | 1.93 | .300 | 1.21 | 7.1 | 3.9 | 9.6 | 14.0 | 11 | 3 | 3 | 1 | 6 | 15 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.29 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 48 | 31 | 0 | 2 | 0 | 4.05 | .241 | 0.95 | 5.0 | 3.6 | 7.2 | 20.0 | 11 | 9 | 9 | 1 | 8 | 16 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 3.25 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 18 | 0 | 1 | 0 | 4.50 | .333 | 1.42 | 10.5 | 2.3 | 6.8 | 12.0 | 14 | 7 | 6 | 2 | 3 | 9 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.67 |
| RP | Fingers, R.Fingers, Rollie >> | 35 | 1981 | R | 53 | 2 | 0 | 0 | 0 | 4.50 | .250 | 1.00 | 2.3 | 6.8 | 6.8 | 4.0 | 1 | 2 | 2 | 0 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.75 |
| SP | Chance, D.Chance, Dean >> | 23 | 1964 | R | 53 | 8 | 5 | 3 | 2 | 7.31 | .319 | 1.41 | 8.4 | 4.2 | 5.3 | 32.0 | 30 | 27 | 26 | 6 | 15 | 19 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 5.66 |