| SP | Kershaw, C.Kershaw, Clayton † >> | 28 | 2016 | L | 99 | 25 | 25 | 11 | 7 | 3.48 | .276 | 1.12 | 8.5 | 1.6 | 8.4 | 199.1 | 189 | 80 | 77 | 18 | 35 | 186 | 8 | 0 | 0 | 0 | 14 | 4 | 4 | 2.89 |
| SP | Gibson, B.Gibson, Bob † >> | 33 | 1968 | R | 93 | 24 | 24 | 12 | 9 | 3.66 | .276 | 1.12 | 7.1 | 3.0 | 6.1 | 192.0 | 151 | 85 | 78 | 22 | 64 | 131 | 11 | 0 | 0 | 2 | 13 | 5 | 2 | 4.20 |
| SP | Seaver, T.Seaver, Tom # >> | 27 | 1971 | R | 71 | 23 | 23 | 9 | 10 | 4.67 | .333 | 1.49 | 9.3 | 4.1 | 7.7 | 160.0 | 166 | 88 | 83 | 20 | 72 | 137 | 4 | 0 | 0 | 0 | 12 | 2 | 2 | 4.30 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 23 | 23 | 9 | 8 | 5.08 | .347 | 1.56 | 10.0 | 4.1 | 7.6 | 156.0 | 173 | 100 | 88 | 22 | 71 | 131 | 1 | 0 | 0 | 0 | 11 | 5 | 4 | 4.62 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 59 | 0 | 4 | 4 | 3.24 | .253 | 0.99 | 5.7 | 3.3 | 9.4 | 77.2 | 49 | 29 | 28 | 3 | 28 | 80 | 0 | 10 | 2 | 0 | 0 | 2 | 1 | 2.60 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 46 | 0 | 5 | 5 | 4.11 | .278 | 1.13 | 6.7 | 3.6 | 10.1 | 50.1 | 37 | 29 | 23 | 11 | 20 | 56 | 0 | 6 | 3 | 0 | 0 | 1 | 0 | 4.88 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 22 | 0 | 4 | 0 | 1.55 | .275 | 1.10 | 6.2 | 3.7 | 7.8 | 29.0 | 20 | 7 | 5 | 2 | 12 | 25 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.52 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 18 | 0 | 2 | 1 | 4.32 | .275 | 1.14 | 9.0 | 1.7 | 10.7 | 16.2 | 16 | 8 | 8 | 4 | 3 | 19 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 4.44 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 13 | 0 | 0 | 0 | 2.40 | .250 | 1.00 | 6.0 | 3.0 | 6.6 | 15.0 | 10 | 4 | 4 | 3 | 5 | 11 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 5.13 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 14 | 0 | 0 | 1 | 2.65 | .190 | 0.71 | 4.8 | 1.6 | 7.4 | 17.0 | 9 | 7 | 5 | 4 | 3 | 14 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.94 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 1 | 0 | 0 | 0 | 0.00 | .333 | 1.50 | - | - | - | 0.2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |