| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 32 | 32 | 12 | 11 | 3.82 | .293 | 1.22 | 7.3 | 3.7 | 4.6 | 202.2 | 164 | 89 | 86 | 25 | 84 | 103 | 2 | 0 | 0 | 1 | 20 | 4 | 6 | 4.90 |
| SP | Brown, M.Brown, Mordecai # >> | 32 | 1908 | R | 85 | 31 | 31 | 10 | 11 | 3.45 | .269 | 1.10 | 7.8 | 2.1 | 4.5 | 237.2 | 206 | 97 | 91 | 15 | 56 | 118 | 8 | 0 | 0 | 2 | 18 | 1 | 4 | 3.55 |
| SP | Greinke, Z.Greinke, Zack # >> | 32 | 2015 | R | 94 | 30 | 30 | 13 | 15 | 4.20 | .301 | 1.26 | 8.7 | 2.6 | 5.9 | 208.0 | 202 | 101 | 97 | 17 | 61 | 136 | 4 | 0 | 0 | 2 | 17 | 6 | 6 | 3.72 |
| SP | Lincecum, T.Lincecum, Tim # >> | 25 | 2009 | R | 41 | 25 | 14 | 9 | 3 | 4.00 | .302 | 1.29 | 8.3 | 3.4 | 7.6 | 132.2 | 121 | 61 | 59 | 10 | 50 | 112 | 3 | 0 | 0 | 3 | 6 | 1 | 5 | 3.45 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 26 | 19 | 8 | 5 | 4.35 | .321 | 1.41 | 10.1 | 2.6 | 7.9 | 151.0 | 169 | 77 | 73 | 26 | 44 | 132 | 0 | 0 | 0 | 0 | 12 | 1 | 1 | 4.38 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 77 | 0 | 1 | 2 | 1.93 | .260 | 1.05 | 7.6 | 1.9 | 7.7 | 56.0 | 47 | 12 | 12 | 4 | 12 | 48 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 2.86 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 37 | 62 | 0 | 3 | 2 | 4.36 | .313 | 1.33 | 6.3 | 5.7 | 6.5 | 33.0 | 23 | 16 | 16 | 2 | 21 | 24 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 4.33 |
| RP | Perkins, G.Perkins, Glen >> | 30 | 2013 | L | 50 | 30 | 0 | 2 | 0 | 3.68 | .298 | 1.23 | 7.8 | 3.3 | 7.8 | 22.0 | 19 | 9 | 9 | 3 | 8 | 19 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 4.27 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 54 | 0 | 2 | 1 | 2.15 | .257 | 1.04 | 7.5 | 1.9 | 8.0 | 37.2 | 31 | 9 | 9 | 4 | 8 | 33 | 0 | 5 | 2 | 0 | 0 | 0 | 0 | 3.27 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 23 | 0 | 4 | 3 | 3.63 | .309 | 1.25 | 7.4 | 4.1 | 8.2 | 22.1 | 18 | 9 | 9 | 4 | 10 | 20 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 5.18 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 51 | 27 | 26 | 8 | 13 | 4.82 | .325 | 1.43 | 9.5 | 3.4 | 4.7 | 179.1 | 188 | 103 | 96 | 14 | 68 | 93 | 3 | 0 | 0 | 1 | 10 | 3 | 4 | 4.17 |