| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 32 | 32 | 10 | 15 | 3.76 | .270 | 1.09 | 7.7 | 2.1 | 9.4 | 201.0 | 172 | 89 | 84 | 31 | 48 | 209 | 0 | 0 | 0 | 0 | 20 | 3 | 0 | 3.69 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 30 | 30 | 6 | 16 | 6.76 | .386 | 1.86 | 14.1 | 2.7 | 5.2 | 151.2 | 236 | 117 | 114 | 17 | 46 | 87 | 0 | 0 | 0 | 0 | 7 | 4 | 1 | 4.30 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 76 | 0 | 1 | 12 | 4.48 | .323 | 1.40 | 8.4 | 4.3 | 10.0 | 78.1 | 73 | 43 | 39 | 11 | 37 | 87 | 0 | 36 | 6 | 0 | 0 | 2 | 3 | 4.10 |
| SU | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 78 | 0 | 2 | 4 | 3.82 | .284 | 1.18 | 7.7 | 3.0 | 7.8 | 94.1 | 80 | 40 | 40 | 11 | 31 | 81 | 0 | 4 | 5 | 0 | 0 | 1 | 1 | 3.82 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 92 | 0 | 8 | 8 | 6.33 | .361 | 1.67 | 10.6 | 4.5 | 8.4 | 106.2 | 125 | 76 | 75 | 20 | 53 | 99 | 0 | 1 | 4 | 0 | 0 | 3 | 1 | 5.17 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 73 | 0 | 3 | 1 | 6.60 | .352 | 1.61 | 10.9 | 3.6 | 7.8 | 75.0 | 91 | 58 | 55 | 20 | 30 | 65 | 0 | 1 | 1 | 0 | 0 | 1 | 4 | 5.97 |