| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 92 | 9 | 9 | 3 | 0 | 3.68 | .320 | 1.37 | 7.7 | 4.7 | 7.3 | 63.2 | 54 | 26 | 26 | 8 | 33 | 51 | 0 | 0 | 0 | 0 | 6 | 3 | 2 | 4.75 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 9 | 9 | 2 | 3 | 5.02 | .322 | 1.42 | 8.1 | 4.7 | 3.8 | 52.0 | 47 | 29 | 29 | 3 | 27 | 22 | 1 | 0 | 0 | 1 | 4 | 0 | 1 | 4.46 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 9 | 8 | 4 | 1 | 3.24 | .282 | 1.15 | 7.5 | 3.1 | 8.3 | 41.2 | 34 | 15 | 15 | 6 | 14 | 38 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 4.15 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 30 | 0 | 2 | 1 | 3.18 | .292 | 1.20 | 7.4 | 3.5 | 8.0 | 28.1 | 23 | 10 | 10 | 3 | 11 | 25 | 0 | 1 | 3 | 0 | 0 | 1 | 1 | 3.89 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 63 | 29 | 0 | 1 | 3 | 2.73 | .240 | 0.91 | 6.6 | 1.7 | 7.6 | 26.1 | 19 | 8 | 8 | 1 | 5 | 22 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 2.50 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 22 | 0 | 0 | 1 | 5.60 | .312 | 1.36 | 9.0 | 3.7 | 5.8 | 17.2 | 17 | 12 | 11 | 1 | 7 | 11 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 3.71 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 54 | 14 | 0 | 1 | 3 | 5.60 | .321 | 1.42 | 9.0 | 4.2 | 9.5 | 17.2 | 17 | 11 | 11 | 4 | 8 | 18 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 5.35 |
| RP | LaRoche, D.LaRoche, Dave >> | 28 | 1976 | L | 33 | 18 | 0 | 0 | 2 | 5.21 | .367 | 1.53 | 7.6 | 6.2 | 5.2 | 19.0 | 16 | 11 | 11 | 0 | 13 | 11 | 0 | 3 | 1 | 0 | 0 | 4 | 0 | 4.53 |