| SP | Kershaw, C.Kershaw, Clayton † >> | 28 | 2016 | L | 99 | 34 | 34 | 13 | 18 | 3.60 | .280 | 1.14 | 8.7 | 1.6 | 8.9 | 237.2 | 228 | 101 | 95 | 33 | 42 | 235 | 8 | 0 | 0 | 2 | 21 | 7 | 4 | 3.45 |
| SP | Iwakuma, H.Iwakuma, Hisashi >> | 32 | 2013 | R | 65 | 33 | 33 | 6 | 13 | 5.69 | .332 | 1.47 | 10.0 | 3.2 | 6.5 | 174.0 | 193 | 115 | 110 | 36 | 62 | 126 | 1 | 0 | 0 | 0 | 14 | 4 | 3 | 5.38 |
| SP | Lackey, J.Lackey, John >> | 38 | 2016 | R | 59 | 32 | 32 | 7 | 17 | 6.31 | .338 | 1.50 | 10.3 | 3.2 | 8.2 | 158.1 | 180 | 114 | 111 | 34 | 57 | 144 | 0 | 0 | 0 | 0 | 12 | 5 | 5 | 5.15 |
| SP | Wainwright, A.Wainwright, Adam >> | 29 | 2010 | R | 55 | 32 | 32 | 13 | 9 | 3.65 | .306 | 1.30 | 8.5 | 3.2 | 7.3 | 214.2 | 203 | 88 | 87 | 30 | 77 | 174 | 4 | 0 | 0 | 2 | 19 | 4 | 3 | 4.33 |
| RP | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 98 | 0 | 6 | 4 | 3.51 | .287 | 1.18 | 7.8 | 2.8 | 10.5 | 130.2 | 113 | 51 | 51 | 24 | 41 | 152 | 0 | 9 | 1 | 0 | 0 | 4 | 1 | 4.10 |
| RP | Miller, A.Miller, Andrew >> | 30 | 2015 | L | 82 | 78 | 0 | 5 | 3 | 3.09 | .289 | 1.21 | 7.3 | 3.6 | 10.3 | 99.0 | 80 | 36 | 34 | 11 | 40 | 113 | 0 | 8 | 2 | 0 | 0 | 1 | 0 | 3.40 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 75 | 64 | 0 | 0 | 4 | 3.32 | .287 | 1.18 | 7.1 | 3.6 | 10.8 | 81.1 | 64 | 30 | 30 | 5 | 32 | 97 | 0 | 3 | 1 | 0 | 0 | 2 | 5 | 2.67 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 51 | 0 | 5 | 1 | 3.65 | .307 | 1.33 | 8.9 | 3.2 | 9.3 | 61.2 | 60 | 25 | 25 | 6 | 22 | 63 | 0 | 3 | 2 | 0 | 0 | 0 | 1 | 3.30 |
| RP | Knebel, C.Knebel, Corey >> | 25 | 2017 | R | 30 | 37 | 0 | 0 | 3 | 3.91 | .352 | 1.61 | 8.6 | 5.9 | 11.2 | 46.0 | 44 | 20 | 20 | 4 | 30 | 57 | 0 | 2 | 2 | 0 | 0 | 1 | 3 | 3.67 |