| SP | Rodon, C.Rodon, Carlos >> | 32 | 2025 | L | 92 | 16 | 16 | 6 | 6 | 3.01 | .290 | 1.22 | 7.3 | 3.8 | 10.0 | 104.2 | 84 | 36 | 35 | 9 | 44 | 115 | 0 | 0 | 0 | 0 | 11 | 0 | 2 | 3.18 |
| SP | Glasnow, T.Glasnow, Tyler >> | 31 | 2025 | R | 88 | 16 | 16 | 2 | 4 | 3.87 | .337 | 1.48 | 7.4 | 5.9 | 10.7 | 81.1 | 67 | 38 | 35 | 11 | 53 | 96 | 0 | 0 | 0 | 0 | 4 | 4 | 5 | 4.51 |
| SP | Valdez, F.Valdez, Framber >> | 31 | 2025 | L | 63 | 16 | 16 | 2 | 9 | 5.91 | .370 | 1.71 | 11.2 | 4.3 | 7.1 | 91.1 | 113 | 63 | 60 | 17 | 43 | 72 | 0 | 0 | 0 | 0 | 5 | 5 | 1 | 5.43 |
| SP | Flaherty, J.Flaherty, Jack >> | 29 | 2025 | R | 57 | 15 | 15 | 3 | 3 | 5.78 | .371 | 1.73 | 11.2 | 4.6 | 8.5 | 71.2 | 88 | 46 | 46 | 9 | 36 | 67 | 0 | 0 | 0 | 0 | 2 | 3 | 1 | 4.41 |
| SP | Cease, D.Cease, Dylan # >> | 29 | 2025 | R | 48 | 15 | 15 | 8 | 3 | 5.11 | .328 | 1.44 | 9.5 | 3.6 | 11.3 | 75.2 | 79 | 43 | 43 | 14 | 30 | 94 | 0 | 0 | 0 | 0 | 2 | 2 | 1 | 4.20 |
| RP | Cleavinger, G.Cleavinger, Garrett >> | 31 | 2025 | L | 93 | 41 | 0 | 2 | 4 | 5.02 | .301 | 1.27 | 7.9 | 3.6 | 10.4 | 57.1 | 50 | 33 | 32 | 4 | 23 | 66 | 0 | 1 | 3 | 0 | 0 | 1 | 0 | 2.86 |
| RP | Estevez, C.Estevez, Carlos >> | 32 | 2025 | R | 69 | 43 | 0 | 0 | 1 | 5.27 | .305 | 1.28 | 8.0 | 3.5 | 7.2 | 56.1 | 50 | 33 | 33 | 6 | 22 | 45 | 0 | 5 | 4 | 0 | 0 | 2 | 0 | 4.07 |
| RP | Stewart, B.Stewart, Brock >> | 33 | 2025 | R | 55 | 41 | 0 | 2 | 3 | 3.44 | .317 | 1.37 | 9.2 | 3.3 | 10.8 | 49.2 | 50 | 22 | 19 | 6 | 18 | 59 | 0 | 2 | 5 | 0 | 0 | 1 | 0 | 3.35 |
| RP | Bummer, A.Bummer, Aaron >> | 31 | 2025 | L | 35 | 24 | 0 | 4 | 2 | 5.16 | .360 | 1.58 | 10.9 | 3.7 | 6.5 | 29.2 | 35 | 17 | 17 | 6 | 12 | 21 | 0 | 1 | 4 | 0 | 0 | 3 | 0 | 5.79 |
| SP | Scherzer, M.Scherzer, Max >> | 41 | 2025 | R | 35 | 2 | 0 | 0 | 0 | 0.00 | .200 | 0.75 | 9.0 | 0.0 | 18.0 | 1.1 | 1 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1.00 |
| SP | Peterson, D.Peterson, David >> | 29 | 2025 | L | 26 | 15 | 0 | 3 | 2 | 6.04 | .356 | 1.66 | 10.2 | 4.9 | 8.6 | 22.1 | 25 | 15 | 15 | 6 | 12 | 21 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 6.27 |