| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 100 | 16 | 16 | 8 | 2 | 3.59 | .319 | 1.40 | 10.2 | 2.4 | 10.4 | 105.1 | 119 | 43 | 42 | 13 | 28 | 121 | 0 | 0 | 0 | 0 | 10 | 1 | 0 | 3.13 |
| SP | Crochet, G.Crochet, Garrett >> | 26 | 2025 | L | 89 | 16 | 16 | 5 | 5 | 4.97 | .330 | 1.45 | 9.1 | 4.1 | 11.4 | 88.2 | 89 | 51 | 49 | 14 | 40 | 111 | 0 | 0 | 0 | 0 | 9 | 2 | 2 | 3.98 |
| SP | Schwellenbach, S.Schwellenbach, Spencer >> | 25 | 2025 | R | 87 | 16 | 16 | 7 | 1 | 4.15 | .284 | 1.16 | 8.2 | 2.3 | 7.8 | 104.0 | 95 | 48 | 48 | 18 | 26 | 90 | 1 | 0 | 0 | 0 | 10 | 3 | 1 | 4.36 |
| SP | Cameron, N.Cameron, Noah >> | 25 | 2025 | L | 81 | 15 | 15 | 4 | 3 | 4.92 | .347 | 1.57 | 9.3 | 4.8 | 8.6 | 82.1 | 85 | 46 | 45 | 13 | 44 | 78 | 0 | 0 | 0 | 0 | 4 | 2 | 0 | 4.84 |
| CL | Svanson, M.Svanson, Matt >> | 26 | 2025 | R | 98 | 33 | 0 | 0 | 2 | 3.48 | .290 | 1.16 | 7.0 | 3.5 | 11.9 | 31.0 | 24 | 12 | 12 | 2 | 12 | 41 | 0 | 26 | 3 | 0 | 0 | 2 | 1 | 2.55 |
| SU | Suarez, R.Suarez, Robert # >> | 34 | 2025 | R | 91 | 31 | 0 | 2 | 5 | 7.79 | .336 | 1.52 | 11.0 | 2.8 | 12.1 | 32.1 | 39 | 31 | 28 | 8 | 10 | 43 | 0 | 1 | 6 | 0 | 0 | 0 | 3 | 4.50 |
| RP | Santana, D.Santana, Dennis >> | 29 | 2025 | R | 92 | 46 | 0 | 2 | 1 | 2.31 | .295 | 1.20 | 8.7 | 2.1 | 10.3 | 35.0 | 34 | 9 | 9 | 4 | 8 | 40 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 3.06 |
| RP | Henriquez, R.Henriquez, Ronny >> | 25 | 2025 | R | 77 | 26 | 0 | 2 | 0 | 3.05 | .303 | 1.31 | 7.2 | 5.0 | 11.7 | 20.2 | 16 | 8 | 7 | 3 | 11 | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.00 |
| RP | Finnegan, K.Finnegan, Kyle >> | 33 | 2025 | R | 65 | 20 | 0 | 5 | 1 | 4.32 | .275 | 1.14 | 6.8 | 3.9 | 9.6 | 16.2 | 12 | 8 | 8 | 2 | 7 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.81 |
| SP | Kershaw, C.Kershaw, Clayton >> | 37 | 2025 | L | 60 | 10 | 0 | 3 | 0 | 3.77 | .301 | 1.29 | 9.0 | 2.6 | 5.8 | 31.0 | 31 | 15 | 13 | 3 | 9 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.84 |