| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 93 | 23 | 23 | 7 | 8 | 3.78 | .283 | 1.17 | 8.0 | 2.6 | 8.1 | 154.2 | 137 | 70 | 65 | 16 | 44 | 138 | 2 | 0 | 0 | 1 | 13 | 2 | 2 | 3.45 |
| SP | Maddux, G.Maddux, Greg † >> | 29 | 1995 | R | 89 | 22 | 22 | 11 | 6 | 3.21 | .272 | 1.10 | 7.8 | 2.1 | 6.3 | 151.1 | 131 | 62 | 54 | 16 | 36 | 106 | 1 | 0 | 0 | 0 | 15 | 3 | 0 | 3.75 |
| SP | Johnson, R.Johnson, Randy # >> | 41 | 2004 | L | 84 | 21 | 21 | 6 | 8 | 5.84 | .350 | 1.60 | 10.9 | 3.6 | 8.2 | 115.2 | 139 | 75 | 75 | 22 | 46 | 105 | 1 | 0 | 0 | 0 | 6 | 2 | 1 | 4.91 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 85 | 62 | 0 | 4 | 3 | 3.97 | .324 | 1.42 | 9.8 | 3.1 | 9.3 | 70.1 | 76 | 34 | 31 | 6 | 24 | 72 | 0 | 2 | 3 | 0 | 0 | 1 | 6 | 3.13 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 51 | 0 | 5 | 2 | 6.23 | .345 | 1.53 | 8.6 | 5.4 | 7.2 | 60.2 | 57 | 42 | 42 | 7 | 36 | 48 | 0 | 0 | 1 | 0 | 0 | 3 | 0 | 4.87 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 52 | 0 | 2 | 2 | 4.60 | .308 | 1.34 | 8.7 | 3.5 | 12.3 | 60.2 | 58 | 32 | 31 | 8 | 23 | 82 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 3.15 |
| RP | Holland, A.Holland, Al >> | 31 | 1983 | L | 34 | 44 | 0 | 3 | 2 | 6.04 | .382 | 1.84 | 10.8 | 5.9 | 7.4 | 44.2 | 53 | 31 | 30 | 6 | 29 | 36 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 5.18 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 57 | 0 | 2 | 6 | 6.60 | .336 | 1.48 | 9.0 | 4.4 | 11.2 | 61.1 | 61 | 45 | 45 | 7 | 30 | 76 | 0 | 20 | 6 | 0 | 0 | 2 | 6 | 3.57 |