| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 22 | 22 | 9 | 7 | 4.12 | .258 | 1.04 | 8.1 | 1.3 | 4.7 | 163.2 | 146 | 77 | 75 | 16 | 24 | 85 | 4 | 0 | 0 | 0 | 11 | 1 | 4 | 3.69 |
| SP | Snell, B.Snell, Blake † $$ >> | 25 | 2018 | L | 81 | 21 | 21 | 11 | 3 | 2.32 | .243 | 0.95 | 5.4 | 3.1 | 8.6 | 136.0 | 82 | 36 | 35 | 11 | 47 | 130 | 0 | 0 | 0 | 0 | 15 | 2 | 4 | 3.22 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 87 | 52 | 0 | 3 | 4 | 3.69 | .261 | 1.03 | 8.0 | 1.3 | 8.7 | 63.1 | 56 | 29 | 26 | 6 | 9 | 61 | 0 | 3 | 2 | 0 | 0 | 2 | 0 | 2.83 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 41 | 0 | 3 | 2 | 2.33 | .280 | 1.16 | 6.9 | 3.8 | 7.8 | 38.2 | 29 | 11 | 10 | 3 | 16 | 33 | 0 | 3 | 1 | 0 | 0 | 0 | 2 | 3.55 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 58 | 16 | 0 | 1 | 3 | 3.13 | .258 | 1.04 | 6.3 | 3.1 | 5.9 | 23.0 | 16 | 8 | 8 | 2 | 8 | 15 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.87 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 49 | 10 | 0 | 1 | 0 | 3.38 | .344 | 1.58 | 12.5 | 2.1 | 8.3 | 13.1 | 18 | 5 | 5 | 2 | 3 | 12 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.85 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 3 | 0 | 0 | 2 | 2.25 | .304 | 1.31 | 6.8 | 5.1 | 5.1 | 16.0 | 12 | 5 | 4 | 0 | 9 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.56 |
| CL | Chapman, A.Chapman, Aroldis † >> | 37 | 2025 | L | 96 | 48 | 0 | 2 | 1 | 3.57 | .267 | 1.07 | 6.8 | 2.9 | 7.9 | 40.1 | 30 | 16 | 16 | 3 | 13 | 35 | 0 | 23 | 4 | 0 | 0 | 1 | 0 | 3.28 |