| SP | Clemens, R.Clemens, Roger >> | 43 | 2005 | R | 94 | 14 | 14 | 9 | 4 | 3.99 | .313 | 1.33 | 8.5 | 3.5 | 6.1 | 88.0 | 83 | 44 | 39 | 7 | 34 | 60 | 0 | 0 | 0 | 0 | 7 | 3 | 2 | 3.93 |
| SP | Weaver, J.Weaver, Jered # >> | 24 | 2006 | R | 83 | 14 | 14 | 5 | 4 | 4.76 | .294 | 1.22 | 9.1 | 2.0 | 6.5 | 90.2 | 91 | 51 | 48 | 15 | 20 | 65 | 0 | 0 | 0 | 0 | 6 | 2 | 1 | 4.46 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 77 | 14 | 14 | 4 | 3 | 4.50 | .327 | 1.43 | 9.9 | 3.0 | 6.4 | 76.0 | 84 | 41 | 38 | 9 | 25 | 54 | 0 | 0 | 0 | 0 | 5 | 2 | 0 | 4.18 |
| SP | Clement, M.Clement, Matt >> | 28 | 2002 | R | 53 | 13 | 13 | 2 | 4 | 8.17 | .389 | 1.89 | 13.2 | 3.8 | 10.7 | 54.0 | 79 | 49 | 49 | 13 | 23 | 64 | 0 | 0 | 0 | 0 | 1 | 1 | 2 | 5.09 |
| CL | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 96 | 25 | 0 | 2 | 2 | 4.00 | .257 | 0.96 | 8.3 | 0.3 | 6.3 | 27.0 | 25 | 12 | 12 | 4 | 1 | 19 | 0 | 14 | 5 | 0 | 0 | 2 | 0 | 3.85 |
| SU | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 86 | 29 | 0 | 1 | 2 | 7.29 | .344 | 1.52 | 11.6 | 2.1 | 8.6 | 21.0 | 27 | 17 | 17 | 6 | 5 | 20 | 0 | 1 | 4 | 0 | 0 | 1 | 0 | 5.67 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 87 | 38 | 0 | 2 | 0 | 4.11 | .313 | 1.37 | 8.0 | 4.3 | 5.9 | 46.0 | 41 | 21 | 21 | 5 | 22 | 30 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 4.54 |
| RP | Hoffman, T.Hoffman, Trevor >> | 42 | 2009 | R | 72 | 26 | 0 | 2 | 1 | 3.60 | .313 | 1.37 | 9.9 | 2.4 | 7.2 | 30.0 | 33 | 12 | 12 | 4 | 8 | 24 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 3.93 |
| RP | Politte, C.Politte, Cliff >> | 31 | 2005 | R | 65 | 21 | 0 | 2 | 2 | 3.32 | .301 | 1.25 | 7.3 | 4.3 | 7.3 | 21.2 | 17 | 9 | 8 | 0 | 10 | 17 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 2.95 |