| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 100 | 29 | 29 | 10 | 12 | 4.19 | .306 | 1.27 | 8.0 | 3.4 | 9.4 | 199.2 | 177 | 93 | 93 | 17 | 76 | 207 | 1 | 0 | 0 | 0 | 18 | 11 | 6 | 3.34 |
| SP | Vazquez, J.Vazquez, Javier † >> | 33 | 2009 | R | 86 | 28 | 28 | 11 | 8 | 4.42 | .303 | 1.27 | 8.8 | 2.6 | 9.3 | 197.1 | 193 | 101 | 97 | 25 | 57 | 204 | 2 | 0 | 0 | 0 | 14 | 7 | 3 | 3.55 |
| SP | Pettitte, A.Pettitte, Andy # >> | 33 | 2005 | L | 78 | 28 | 28 | 10 | 13 | 4.65 | .325 | 1.41 | 9.3 | 3.4 | 5.6 | 184.0 | 190 | 103 | 95 | 25 | 69 | 115 | 2 | 0 | 0 | 0 | 15 | 7 | 4 | 4.76 |
| SP | Garcia, F.Garcia, Freddy # >> | 26 | 2001 | R | 61 | 27 | 26 | 16 | 8 | 4.28 | .296 | 1.23 | 8.3 | 2.8 | 6.3 | 181.0 | 166 | 87 | 86 | 23 | 57 | 127 | 7 | 0 | 0 | 3 | 16 | 5 | 1 | 4.28 |
| RP | Foulke, K.Foulke, Keith >> | 31 | 2003 | R | 78 | 55 | 0 | 5 | 2 | 2.94 | .228 | 0.87 | 5.8 | 2.1 | 10.3 | 64.1 | 41 | 21 | 21 | 8 | 15 | 73 | 0 | 4 | 1 | 0 | 0 | 1 | 0 | 3.09 |
| RP | Perez, R.Perez, Rafael >> | 25 | 2007 | L | 65 | 77 | 0 | 1 | 0 | 3.50 | .322 | 1.37 | 7.8 | 4.5 | 9.8 | 54.0 | 47 | 23 | 21 | 8 | 27 | 59 | 0 | 1 | 1 | 0 | 0 | 3 | 3 | 4.41 |
| RP | Rodriguez, F.Rodriguez, Felix >> | 29 | 2001 | R | 59 | 41 | 0 | 1 | 4 | 3.11 | .302 | 1.27 | 6.3 | 5.3 | 9.4 | 46.1 | 32 | 21 | 16 | 6 | 27 | 48 | 0 | 3 | 1 | 0 | 0 | 1 | 2 | 4.43 |