| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 26 | 26 | 12 | 5 | 2.74 | .269 | 1.10 | 7.7 | 2.2 | 8.7 | 161.0 | 137 | 53 | 49 | 16 | 40 | 155 | 0 | 0 | 0 | 0 | 13 | 1 | 0 | 3.13 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 25 | 25 | 7 | 10 | 5.33 | .351 | 1.59 | 9.7 | 4.7 | 7.1 | 121.2 | 131 | 77 | 72 | 13 | 63 | 95 | 0 | 0 | 0 | 0 | 4 | 3 | 2 | 4.46 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 25 | 25 | 5 | 8 | 4.20 | .321 | 1.39 | 10.3 | 2.2 | 5.9 | 154.1 | 177 | 78 | 72 | 10 | 38 | 101 | 2 | 0 | 0 | 0 | 13 | 4 | 1 | 3.35 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 64 | 0 | 5 | 2 | 4.02 | .316 | 1.38 | 9.8 | 2.7 | 7.4 | 80.2 | 87 | 39 | 36 | 14 | 24 | 66 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 4.56 |
| RP | Foulke, K.Foulke, Keith # >> | 27 | 1999 | R | 59 | 51 | 0 | 1 | 5 | 6.92 | .371 | 1.77 | 12.5 | 3.5 | 9.3 | 52.0 | 72 | 44 | 40 | 11 | 20 | 54 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.83 |
| RP | O'Day, D.O'Day, Darren >> | 28 | 2010 | R | 50 | 40 | 0 | 3 | 1 | 3.92 | .280 | 1.17 | 8.2 | 2.5 | 5.2 | 43.2 | 39 | 20 | 19 | 8 | 12 | 25 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.09 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 49 | 9 | 0 | 3 | 1 | 5.60 | .329 | 1.47 | 11.6 | 2.1 | 10.1 | 17.2 | 22 | 11 | 11 | 2 | 4 | 19 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |