| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 26 | 26 | 7 | 10 | 3.68 | .297 | 1.23 | 7.6 | 3.5 | 7.9 | 185.2 | 156 | 82 | 76 | 14 | 72 | 162 | 6 | 0 | 0 | 1 | 18 | 7 | 0 | 3.51 |
| SP | Nelson, R.Nelson, Roger # >> | 28 | 1972 | R | 84 | 25 | 25 | 8 | 5 | 3.65 | .307 | 1.31 | 9.0 | 2.8 | 6.4 | 133.1 | 133 | 54 | 54 | 19 | 42 | 94 | 0 | 0 | 0 | 0 | 10 | 2 | 1 | 4.44 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 24 | 24 | 4 | 10 | 6.33 | .369 | 1.74 | 10.0 | 5.7 | 8.0 | 123.2 | 137 | 87 | 87 | 20 | 78 | 110 | 0 | 0 | 0 | 0 | 8 | 2 | 1 | 5.28 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 24 | 24 | 9 | 11 | 5.56 | .344 | 1.51 | 10.4 | 3.2 | 4.9 | 147.1 | 170 | 93 | 91 | 19 | 52 | 80 | 3 | 0 | 0 | 0 | 11 | 10 | 2 | 4.86 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 63 | 0 | 4 | 4 | 3.36 | .322 | 1.39 | 7.6 | 4.9 | 9.5 | 83.0 | 70 | 34 | 31 | 7 | 45 | 88 | 0 | 3 | 5 | 0 | 0 | 3 | 1 | 3.71 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 56 | 0 | 6 | 7 | 3.57 | .284 | 1.19 | 8.5 | 2.3 | 10.2 | 75.2 | 71 | 33 | 30 | 8 | 19 | 85 | 0 | 4 | 3 | 0 | 0 | 0 | 0 | 2.88 |
| RP | Gallegos, G.Gallegos, Giovanny # >> | 27 | 2019 | R | 82 | 33 | 0 | 3 | 3 | 4.81 | .302 | 1.30 | 8.5 | 3.2 | 6.2 | 39.1 | 37 | 21 | 21 | 4 | 14 | 27 | 0 | 3 | 1 | 0 | 0 | 0 | 1 | 4.03 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 24 | 1983 | R | 61 | 32 | 0 | 1 | 0 | 5.55 | .314 | 1.35 | 7.5 | 4.9 | 5.7 | 35.2 | 29 | 24 | 22 | 5 | 19 | 22 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.31 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 11 | 0 | 1 | 0 | 4.97 | .296 | 1.26 | 8.3 | 3.8 | 10.5 | 12.2 | 11 | 7 | 7 | 2 | 5 | 14 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 4.08 |