| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 21 | 21 | 7 | 7 | 3.54 | .287 | 1.19 | 8.4 | 2.4 | 9.0 | 134.2 | 125 | 59 | 53 | 22 | 35 | 134 | 0 | 0 | 0 | 0 | 14 | 3 | 0 | 3.99 |
| SP | McNally, D.McNally, Dave † >> | 26 | 1968 | L | 96 | 20 | 20 | 8 | 10 | 3.69 | .309 | 1.33 | 9.3 | 2.7 | 5.2 | 151.1 | 156 | 72 | 62 | 17 | 46 | 88 | 7 | 0 | 0 | 1 | 13 | 1 | 3 | 4.23 |
| SP | Walsh, E.Walsh, Ed † # >> | 29 | 1910 | R | 93 | 20 | 20 | 11 | 5 | 3.02 | .260 | 1.04 | 7.5 | 1.8 | 4.2 | 164.0 | 137 | 63 | 55 | 15 | 33 | 77 | 13 | 0 | 0 | 1 | 14 | 3 | 2 | 3.91 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 19 | 19 | 5 | 11 | 5.26 | .317 | 1.37 | 9.4 | 3.0 | 3.7 | 128.1 | 134 | 80 | 75 | 15 | 42 | 52 | 2 | 0 | 0 | 1 | 8 | 3 | 6 | 4.77 |
| RP | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 50 | 0 | 5 | 3 | 3.28 | .267 | 1.05 | 5.4 | 4.1 | 8.3 | 68.2 | 41 | 28 | 25 | 8 | 31 | 63 | 0 | 9 | 0 | 0 | 0 | 3 | 0 | 4.18 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 14 | 0 | 1 | 0 | 2.89 | .273 | 1.13 | 5.5 | 5.0 | 8.0 | 18.2 | 11 | 6 | 6 | 0 | 10 | 16 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.89 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 12 | 0 | 0 | 0 | 4.91 | .313 | 1.36 | 6.4 | 6.4 | 8.4 | 14.2 | 10 | 9 | 8 | 2 | 10 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 5.14 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 3 | 2 | 1 | 1 | 3.38 | .286 | 1.13 | 8.3 | 2.1 | 11.1 | 13.1 | 12 | 5 | 5 | 3 | 3 | 16 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 4.46 |