| SP | Martinez, P.Martinez, Pedro † # >> | 29 | 2000 | R | 100 | 27 | 27 | 14 | 5 | 2.93 | .250 | 0.97 | 6.8 | 1.9 | 8.7 | 199.1 | 151 | 65 | 65 | 15 | 43 | 192 | 6 | 0 | 0 | 5 | 20 | 5 | 4 | 2.77 |
| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 26 | 26 | 10 | 11 | 3.92 | .290 | 1.19 | 8.8 | 2.0 | 5.2 | 176.2 | 172 | 85 | 77 | 20 | 39 | 102 | 5 | 0 | 0 | 1 | 14 | 6 | 2 | 4.09 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 25 | 25 | 9 | 9 | 5.21 | .328 | 1.45 | 9.2 | 3.9 | 8.9 | 148.2 | 151 | 87 | 86 | 22 | 64 | 146 | 0 | 0 | 0 | 0 | 11 | 3 | 6 | 4.32 |
| SP | Sutton, D.Sutton, Don # >> | 27 | 1972 | R | 82 | 23 | 23 | 6 | 9 | 5.35 | .336 | 1.50 | 10.4 | 3.1 | 6.4 | 153.0 | 177 | 94 | 91 | 22 | 53 | 109 | 5 | 0 | 0 | 1 | 8 | 2 | 5 | 4.52 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 73 | 0 | 6 | 2 | 4.04 | .270 | 1.11 | 7.6 | 2.4 | 8.9 | 71.1 | 60 | 32 | 32 | 8 | 19 | 70 | 0 | 3 | 4 | 0 | 0 | 0 | 0 | 3.30 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 36 | 0 | 1 | 6 | 8.54 | .397 | 1.97 | 11.1 | 6.7 | 8.1 | 39.0 | 48 | 37 | 37 | 8 | 29 | 35 | 0 | 2 | 4 | 0 | 0 | 0 | 0 | 6.10 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 33 | 0 | 3 | 0 | 4.66 | .313 | 1.36 | 9.0 | 3.5 | 8.3 | 36.2 | 36 | 19 | 19 | 7 | 14 | 33 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.86 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 12 | 2 | 3 | 2 | 4.45 | .353 | 1.61 | 12.1 | 2.5 | 7.0 | 32.1 | 43 | 17 | 16 | 3 | 9 | 25 | 0 | 2 | 0 | 0 | 2 | 1 | 1 | 3.59 |