| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 21 | 21 | 9 | 4 | 4.00 | .294 | 1.24 | 8.7 | 2.4 | 9.0 | 144.0 | 139 | 68 | 64 | 10 | 39 | 144 | 2 | 0 | 0 | 2 | 12 | 2 | 1 | 2.76 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 21 | 21 | 5 | 9 | 5.17 | .303 | 1.27 | 8.4 | 3.0 | 8.5 | 134.0 | 125 | 77 | 77 | 20 | 45 | 127 | 1 | 0 | 0 | 1 | 6 | 5 | 2 | 4.16 |
| SP | Greinke, Z.Greinke, Zack † >> | 32 | 2015 | R | 94 | 20 | 20 | 8 | 7 | 3.35 | .277 | 1.14 | 8.4 | 1.9 | 5.5 | 145.0 | 135 | 73 | 54 | 14 | 31 | 88 | 5 | 0 | 0 | 2 | 13 | 1 | 2 | 3.70 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 20 | 20 | 7 | 9 | 5.21 | .328 | 1.44 | 9.1 | 3.9 | 9.3 | 114.0 | 115 | 68 | 66 | 13 | 49 | 118 | 0 | 0 | 0 | 0 | 8 | 3 | 2 | 3.78 |
| RP | Street, H.Street, Huston † >> | 29 | 2012 | R | 96 | 60 | 0 | 6 | 3 | 3.82 | .309 | 1.31 | 7.8 | 4.1 | 8.3 | 77.2 | 67 | 40 | 33 | 6 | 35 | 71 | 0 | 6 | 4 | 0 | 0 | 2 | 2 | 3.61 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 50 | 0 | 2 | 3 | 5.63 | .332 | 1.46 | 8.6 | 4.6 | 9.3 | 62.1 | 59 | 39 | 39 | 8 | 32 | 64 | 0 | 6 | 2 | 0 | 0 | 2 | 2 | 4.26 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 46 | 0 | 4 | 4 | 5.51 | .309 | 1.30 | 8.3 | 3.6 | 8.5 | 50.2 | 46 | 31 | 31 | 8 | 20 | 47 | 0 | 4 | 4 | 0 | 0 | 2 | 1 | 4.52 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 36 | 0 | 3 | 1 | 7.18 | .377 | 1.71 | 11.5 | 4.0 | 5.8 | 36.1 | 46 | 30 | 29 | 5 | 16 | 23 | 0 | 4 | 4 | 0 | 0 | 4 | 3 | 5.19 |