| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 21 | 21 | 6 | 9 | 6.81 | .390 | 1.90 | 12.5 | 4.7 | 4.4 | 120.1 | 166 | 108 | 91 | 21 | 63 | 59 | 0 | 0 | 0 | 0 | 6 | 2 | 7 | 5.92 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 21 | 21 | 8 | 8 | 4.90 | .335 | 1.49 | 10.1 | 3.3 | 7.6 | 132.1 | 148 | 75 | 72 | 19 | 49 | 111 | 1 | 0 | 0 | 1 | 7 | 3 | 2 | 4.37 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 21 | 21 | 8 | 11 | 4.68 | .330 | 1.47 | 9.7 | 3.5 | 5.3 | 152.0 | 164 | 89 | 79 | 14 | 59 | 89 | 5 | 0 | 0 | 1 | 9 | 2 | 7 | 4.23 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 63 | 0 | 4 | 4 | 5.06 | .314 | 1.36 | 7.4 | 5.0 | 5.2 | 83.2 | 68 | 50 | 47 | 12 | 46 | 48 | 0 | 4 | 3 | 0 | 0 | 1 | 0 | 5.42 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 52 | 0 | 2 | 5 | 4.36 | .315 | 1.38 | 7.2 | 5.2 | 8.7 | 66.0 | 53 | 34 | 32 | 13 | 38 | 64 | 0 | 7 | 3 | 0 | 0 | 0 | 0 | 5.35 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 39 | 0 | 2 | 3 | 4.32 | .315 | 1.38 | 6.5 | 5.9 | 8.6 | 50.0 | 36 | 25 | 24 | 4 | 33 | 48 | 0 | 2 | 3 | 0 | 0 | 0 | 2 | 4.10 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 32 | 0 | 2 | 2 | 3.52 | .348 | 1.60 | 6.6 | 8.1 | 8.4 | 30.2 | 22 | 13 | 12 | 3 | 27 | 28 | 0 | 2 | 2 | 0 | 0 | 0 | 1 | 5.13 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 28 | 0 | 0 | 1 | 5.20 | .371 | 1.73 | 7.0 | 9.0 | 7.0 | 27.2 | 21 | 16 | 16 | 2 | 27 | 21 | 0 | 0 | 1 | 0 | 0 | 1 | 4 | 5.52 |