| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 95 | 33 | 33 | 7 | 13 | 3.58 | .281 | 1.15 | 7.9 | 2.4 | 8.1 | 236.1 | 208 | 100 | 94 | 30 | 64 | 212 | 2 | 0 | 0 | 0 | 22 | 5 | 9 | 3.73 |
| SP | Blyleven, B.Blyleven, Bert >> | 22 | 1973 | R | 18 | 32 | 32 | 13 | 11 | 4.46 | .312 | 1.35 | 9.6 | 2.6 | 5.6 | 244.0 | 259 | 127 | 121 | 22 | 70 | 151 | 8 | 0 | 0 | 0 | 15 | 3 | 9 | 3.83 |
| RP | Reyes, D.Reyes, Dennys >> | 29 | 2006 | L | 69 | 55 | 0 | 2 | 6 | 3.65 | .291 | 1.22 | 6.5 | 4.6 | 5.2 | 61.2 | 44 | 30 | 25 | 5 | 31 | 35 | 0 | 3 | 5 | 0 | 0 | 1 | 8 | 4.49 |
| RP | Guardado, E.Guardado, Eddie >> | 32 | 2002 | L | 44 | 61 | 0 | 9 | 3 | 3.78 | .283 | 1.17 | 8.6 | 2.0 | 7.5 | 66.2 | 63 | 29 | 28 | 8 | 15 | 55 | 0 | 0 | 5 | 0 | 0 | 1 | 0 | 3.64 |
| RP | Guthrie, M.Guthrie, Mark >> | 27 | 1992 | L | 35 | 33 | 0 | 0 | 2 | 3.95 | .281 | 1.17 | 6.6 | 4.0 | 7.9 | 41.0 | 30 | 19 | 18 | 7 | 18 | 36 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.78 |
| RP | Corbett, D.Corbett, Doug >> | 28 | 1980 | R | 42 | 13 | 0 | 1 | 3 | 6.10 | .333 | 1.50 | 10.4 | 3.6 | 5.4 | 20.2 | 23 | 16 | 14 | 3 | 8 | 12 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 4.95 |
| RP | Perranoski, R.Perranoski, Ron >> | 33 | 1969 | L | 32 | 25 | 0 | 2 | 2 | 3.28 | .277 | 1.12 | 8.5 | 1.8 | 5.1 | 35.2 | 33 | 15 | 13 | 2 | 7 | 20 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.29 |
| SP | Erickson, S.Erickson, Scott >> | 23 | 1991 | R | 1 | 5 | 0 | 0 | 1 | 4.71 | .315 | 1.38 | 9.4 | 3.0 | 6.4 | 21.0 | 22 | 11 | 11 | 3 | 7 | 15 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.43 |