| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 96 | 33 | 33 | 13 | 17 | 3.51 | .285 | 1.19 | 8.7 | 2.0 | 5.0 | 256.1 | 247 | 109 | 100 | 13 | 58 | 143 | 9 | 0 | 0 | 2 | 20 | 2 | 2 | 3.25 |
| SP | Brown, M.Brown, Mordecai >> | 33 | 1909 | R | 87 | 33 | 33 | 17 | 11 | 3.87 | .300 | 1.27 | 8.9 | 2.5 | 4.7 | 237.0 | 235 | 114 | 102 | 11 | 67 | 125 | 5 | 0 | 0 | 1 | 20 | 2 | 4 | 3.42 |
| SP | Reulbach, E.Reulbach, Ed >> | 23 | 1905 | R | 82 | 32 | 32 | 13 | 13 | 4.49 | .305 | 1.30 | 9.2 | 2.5 | 5.0 | 244.1 | 249 | 133 | 122 | 30 | 68 | 135 | 7 | 0 | 0 | 4 | 15 | 4 | 0 | 4.38 |
| SP | Jenkins, F.Jenkins, Fergie >> | 26 | 1968 | R | 46 | 32 | 32 | 14 | 11 | 3.99 | .302 | 1.29 | 9.0 | 2.6 | 5.7 | 239.0 | 239 | 117 | 106 | 19 | 70 | 152 | 8 | 0 | 0 | 1 | 17 | 1 | 2 | 3.65 |
| SP | Warneke, L.Warneke, Lon >> | 23 | 1932 | R | 11 | 32 | 32 | 12 | 16 | 5.16 | .336 | 1.51 | 10.5 | 3.2 | 4.5 | 240.2 | 280 | 144 | 138 | 25 | 84 | 120 | 7 | 0 | 0 | 0 | 10 | 1 | 3 | 4.42 |
| RP | Samardzija, J.Samardzija, Jeff >> | 26 | 2011 | R | 23 | 37 | 0 | 4 | 3 | 2.68 | .280 | 1.12 | 5.9 | 4.3 | 5.9 | 40.1 | 26 | 18 | 12 | 7 | 19 | 26 | 0 | 2 | 2 | 0 | 0 | 2 | 2 | 5.55 |
| RP | Borowski, J.Borowski, Joe >> | 31 | 2002 | R | 20 | 20 | 0 | 1 | 1 | 1.78 | .232 | 0.87 | 6.1 | 1.8 | 6.8 | 25.1 | 17 | 5 | 5 | 1 | 5 | 19 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.72 |
| RP | Farnsworth, K.Farnsworth, Kyle >> | 25 | 2001 | R | 31 | 14 | 0 | 2 | 0 | 4.15 | .291 | 1.23 | 8.3 | 2.8 | 9.7 | 13.0 | 12 | 6 | 6 | 3 | 4 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 4.77 |
| RP | Lancaster, L.Lancaster, Les >> | 27 | 1989 | R | 38 | 20 | 0 | 0 | 2 | 4.60 | .318 | 1.36 | 9.6 | 2.8 | 6.2 | 29.1 | 31 | 15 | 15 | 6 | 9 | 20 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 5.34 |
| SP | Holtzman, K.Holtzman, Ken >> | 22 | 1967 | L | 9 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| CL | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 88 | 45 | 0 | 1 | 2 | 3.51 | .285 | 1.15 | 8.8 | 1.5 | 8.3 | 41.0 | 40 | 16 | 16 | 2 | 7 | 38 | 0 | 36 | 4 | 0 | 0 | 2 | 1 | 2.44 |