| SP | Verlander, J.Verlander, Justin >> | 28 | 2011 | R | 94 | 33 | 33 | 18 | 9 | 3.69 | .296 | 1.25 | 8.3 | 3.0 | 6.4 | 254.0 | 233 | 115 | 104 | 24 | 84 | 182 | 6 | 0 | 0 | 2 | 20 | 4 | 7 | 3.83 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 90 | 33 | 33 | 17 | 10 | 3.39 | .274 | 1.11 | 8.0 | 2.0 | 5.7 | 278.2 | 248 | 117 | 105 | 25 | 62 | 175 | 14 | 0 | 0 | 3 | 19 | 5 | 7 | 3.63 |
| SP | Scherzer, M.Scherzer, Max >> | 29 | 2013 | R | 89 | 32 | 32 | 16 | 8 | 3.79 | .318 | 1.38 | 9.1 | 3.4 | 7.9 | 221.0 | 223 | 107 | 93 | 21 | 83 | 194 | 5 | 0 | 0 | 2 | 19 | 3 | 6 | 3.65 |
| SP | Newhouser, H.Newhouser, Hal >> | 25 | 1946 | L | 57 | 32 | 32 | 13 | 13 | 4.31 | .321 | 1.40 | 8.5 | 4.2 | 5.3 | 246.2 | 231 | 125 | 118 | 18 | 115 | 146 | 11 | 0 | 0 | 3 | 15 | 4 | 4 | 4.22 |
| SP | Bunning, J.Bunning, Jim >> | 26 | 1957 | R | 40 | 32 | 32 | 13 | 11 | 5.06 | .343 | 1.54 | 10.2 | 3.6 | 5.2 | 194.0 | 220 | 118 | 109 | 27 | 78 | 112 | 1 | 0 | 0 | 0 | 14 | 6 | 1 | 4.95 |
| RP | Hernandez, W.Hernandez, Willie >> | 30 | 1984 | L | 72 | 81 | 0 | 8 | 5 | 2.74 | .290 | 1.21 | 7.9 | 3.0 | 4.6 | 128.1 | 113 | 44 | 39 | 9 | 42 | 66 | 0 | 15 | 3 | 0 | 0 | 2 | 3 | 3.91 |
| RP | Hiller, J.Hiller, John >> | 30 | 1973 | L | 61 | 53 | 0 | 5 | 6 | 2.94 | .276 | 1.13 | 6.9 | 3.3 | 6.8 | 79.2 | 61 | 31 | 26 | 9 | 29 | 60 | 0 | 11 | 2 | 0 | 0 | 1 | 2 | 4.10 |
| RP | Zumaya, J.Zumaya, Joel >> | 22 | 2006 | R | 47 | 24 | 0 | 3 | 3 | 1.40 | .274 | 1.13 | 6.8 | 3.6 | 6.8 | 25.2 | 19 | 6 | 4 | 1 | 10 | 19 | 0 | 6 | 1 | 0 | 0 | 0 | 0 | 3.20 |
| RP | Gladding, F.Gladding, Fred >> | 31 | 1967 | R | 41 | 10 | 0 | 1 | 1 | 8.31 | .422 | 2.19 | 18.0 | 3.4 | 10.1 | 8.2 | 16 | 8 | 8 | 0 | 3 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 1.88 |
| RP | Henneman, M.Henneman, Mike >> | 27 | 1988 | R | 38 | 9 | 0 | 0 | 1 | 4.09 | .353 | 1.55 | 9.8 | 4.1 | 4.9 | 11.0 | 12 | 5 | 5 | 1 | 5 | 6 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.73 |
| RP | Valverde, J.Valverde, Jose >> | 32 | 2011 | R | 32 | 12 | 0 | 0 | 0 | 2.61 | .340 | 1.55 | 11.7 | 2.7 | 7.2 | 10.1 | 13 | 5 | 3 | 0 | 3 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.30 |
| RP | Rodney, F.Rodney, Fernando >> | 29 | 2006 | R | 29 | 16 | 0 | 1 | 0 | 4.86 | .375 | 1.80 | 11.3 | 5.6 | 1.7 | 16.2 | 20 | 12 | 9 | 1 | 10 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.31 |
| SP | Lolich, M.Lolich, Mickey >> | 32 | 1972 | L | 29 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Morris, J.Morris, Jack >> | 26 | 1981 | R | 22 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |