| SP | Eovaldi, N.Eovaldi, Nathan >> | 35 | 2025 | R | 99 | 21 | 21 | 8 | 8 | 4.15 | .296 | 1.24 | 8.7 | 2.4 | 4.8 | 130.0 | 126 | 69 | 60 | 17 | 35 | 70 | 0 | 0 | 0 | 0 | 12 | 3 | 3 | 4.50 |
| SP | deGrom, J.deGrom, Jacob >> | 37 | 2025 | R | 93 | 19 | 19 | 8 | 7 | 3.72 | .271 | 1.11 | 7.7 | 2.3 | 7.5 | 121.0 | 103 | 58 | 50 | 18 | 31 | 101 | 2 | 0 | 0 | 0 | 12 | 1 | 1 | 4.06 |
| SP | Darvish, Y.Darvish, Yu # >> | 26 | 2013 | R | 74 | 17 | 17 | 10 | 4 | 3.85 | .301 | 1.26 | 8.3 | 3.1 | 9.0 | 110.0 | 101 | 55 | 47 | 9 | 38 | 110 | 0 | 0 | 0 | 0 | 10 | 3 | 1 | 3.18 |
| SP | Scherzer, M.Scherzer, Max >> | 39 | 2023 | R | 98 | 20 | 16 | 0 | 1 | 4.76 | .333 | 1.48 | 8.8 | 4.7 | 6.9 | 56.2 | 55 | 34 | 30 | 6 | 29 | 43 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.46 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 42 | 0 | 9 | 0 | 2.03 | .259 | 1.05 | 5.6 | 4.0 | 9.3 | 66.2 | 41 | 17 | 15 | 6 | 29 | 68 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 3.44 |
| CL | Uehara, K.Uehara, Koji † >> | 37 | 2012 | R | 93 | 30 | 0 | 2 | 0 | 2.36 | .264 | 1.05 | 6.9 | 2.6 | 9.5 | 34.1 | 26 | 9 | 9 | 2 | 10 | 36 | 0 | 22 | 2 | 0 | 0 | 1 | 0 | 2.62 |
| RP | Leclerc, J.Leclerc, Jose >> | 24 | 2018 | R | 88 | 42 | 0 | 10 | 2 | 2.22 | .306 | 1.27 | 6.1 | 5.5 | 8.4 | 56.2 | 38 | 16 | 14 | 1 | 34 | 52 | 0 | 0 | 2 | 0 | 0 | 3 | 0 | 3.36 |
| RP | Armstrong, S.Armstrong, Shawn >> | 34 | 2025 | R | 81 | 32 | 0 | 2 | 1 | 3.86 | .325 | 1.45 | 9.7 | 3.4 | 5.6 | 37.1 | 40 | 23 | 16 | 3 | 14 | 23 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 3.95 |
| RP | Soria, J.Soria, Joakim >> | 30 | 2014 | R | 58 | 20 | 0 | 0 | 0 | 2.55 | .282 | 1.18 | 7.9 | 3.0 | 8.6 | 24.2 | 21 | 9 | 7 | 2 | 8 | 23 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.17 |
| SP | Augustine, J.Augustine, Jerry >> | 26 | 1978 | L | 16 | 6 | 5 | 2 | 1 | 6.49 | .373 | 1.78 | 13.2 | 3.1 | 2.4 | 26.1 | 38 | 19 | 19 | 2 | 9 | 7 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 4.50 |