| SP | Foster, R.Foster, Rube >> | 26 | 1914 | R | 50 | 6 | 6 | 3 | 2 | 4.54 | .346 | 1.59 | 11.1 | 3.5 | 3.9 | 39.2 | 48 | 20 | 20 | 2 | 15 | 17 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 3.95 |
| SP | Leonard, D.Leonard, Dutch >> | 23 | 1915 | L | 56 | 5 | 5 | 2 | 2 | 5.33 | .345 | 1.58 | 9.4 | 5.0 | 5.8 | 25.1 | 26 | 16 | 15 | 1 | 14 | 16 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 3.92 |
| SP | Wakefield, T.Wakefield, Tim >> | 36 | 2002 | R | 58 | 5 | 5 | 1 | 1 | 1.64 | .267 | 1.05 | 6.5 | 2.9 | 5.3 | 22.0 | 16 | 6 | 4 | 1 | 7 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.50 |
| SP | Winter, G.Winter, George >> | 29 | 1907 | R | 49 | 5 | 5 | 1 | 2 | 6.90 | .357 | 1.60 | 9.6 | 4.8 | 5.4 | 30.0 | 32 | 23 | 23 | 6 | 16 | 18 | 0 | 0 | 0 | 0 | 2 | 2 | 1 | 6.20 |
| SU | Uehara, K.Uehara, Koji >> | 40 | 2015 | R | 61 | 9 | 0 | 0 | 0 | 3.48 | .225 | 0.87 | 6.3 | 1.8 | 3.6 | 10.1 | 7 | 4 | 4 | 1 | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.10 |
| CL | Slaten, J.Slaten, Justin >> | 26 | 2024 | R | 29 | 9 | 0 | 1 | 1 | 2.79 | .275 | 1.03 | 8.0 | 2.0 | 10.0 | 9.2 | 8 | 3 | 3 | 0 | 2 | 10 | 0 | 4 | 1 | 0 | 0 | 1 | 0 | 1.78 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 31 | 2011 | R | 53 | 13 | 0 | 2 | 2 | 3.38 | .360 | 1.69 | 11.8 | 3.4 | 10.1 | 16.0 | 21 | 6 | 6 | 1 | 6 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.69 |
| RP | Brasier, R.Brasier, Ryan >> | 30 | 2018 | R | 82 | 4 | 0 | 0 | 0 | 7.20 | .286 | 1.20 | 7.2 | 3.6 | 7.2 | 5.0 | 4 | 4 | 4 | 0 | 2 | 4 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.60 |
| RP | Atchison, S.Atchison, Scott >> | 36 | 2012 | R | 30 | 6 | 0 | 0 | 0 | 5.06 | .385 | 1.69 | 9.0 | 7.2 | 7.2 | 5.1 | 5 | 3 | 3 | 0 | 4 | 4 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 4.40 |