| SP | Foster, R.Foster, Rube >> | 26 | 1914 | R | 64 | 19 | 19 | 4 | 11 | 4.92 | .332 | 1.48 | 9.8 | 3.7 | 4.4 | 120.2 | 130 | 69 | 66 | 14 | 49 | 58 | 3 | 0 | 0 | 0 | 11 | 1 | 0 | 4.80 |
| SP | Wakefield, T.Wakefield, Tim # >> | 37 | 2003 | R | 34 | 20 | 20 | 3 | 13 | 6.99 | .356 | 1.65 | 10.8 | 4.0 | 6.3 | 94.0 | 113 | 75 | 73 | 17 | 42 | 66 | 0 | 0 | 0 | 0 | 4 | 1 | 3 | 5.32 |
| SP | Pennock, H.Pennock, Herb >> | 26 | 1920 | L | 31 | 19 | 19 | 4 | 8 | 5.97 | .351 | 1.63 | 11.6 | 3.0 | 4.2 | 104.0 | 134 | 71 | 69 | 11 | 35 | 48 | 1 | 0 | 0 | 0 | 8 | 0 | 0 | 4.46 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 64 | 0 | 3 | 1 | 3.51 | .278 | 1.15 | 8.5 | 1.9 | 8.6 | 84.2 | 79 | 33 | 33 | 6 | 18 | 80 | 0 | 6 | 4 | 0 | 0 | 1 | 0 | 2.70 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 29 | 2017 | R | 98 | 61 | 0 | 4 | 1 | 2.84 | .261 | 1.06 | 6.2 | 3.4 | 10.5 | 85.2 | 59 | 27 | 27 | 6 | 32 | 99 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 2.72 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 57 | 0 | 7 | 8 | 4.02 | .297 | 1.25 | 7.6 | 3.8 | 9.5 | 69.1 | 58 | 31 | 31 | 3 | 29 | 73 | 0 | 4 | 4 | 0 | 0 | 1 | 4 | 2.75 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 29 | 2009 | R | 37 | 50 | 0 | 2 | 4 | 6.86 | .392 | 1.92 | 12.2 | 5.0 | 9.2 | 59.0 | 80 | 51 | 45 | 11 | 33 | 60 | 0 | 5 | 1 | 0 | 0 | 1 | 0 | 5.12 |
| RP | Fornieles, M.Fornieles, Mike >> | 28 | 1960 | R | 27 | 44 | 0 | 2 | 1 | 5.12 | .346 | 1.55 | 8.9 | 5.1 | 4.7 | 65.0 | 64 | 38 | 37 | 9 | 37 | 34 | 0 | 2 | 0 | 0 | 0 | 2 | 2 | 5.55 |