| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 99 | 15 | 15 | 4 | 7 | 3.49 | .295 | 1.23 | 7.0 | 4.1 | 10.2 | 98.0 | 76 | 41 | 38 | 15 | 45 | 111 | 1 | 0 | 0 | 0 | 11 | 2 | 2 | 4.16 |
| SP | Weaver, J.Weaver, Jered # >> | 29 | 2011 | R | 69 | 15 | 15 | 5 | 5 | 4.81 | .302 | 1.29 | 9.4 | 2.3 | 8.3 | 91.2 | 95 | 49 | 49 | 16 | 23 | 84 | 2 | 0 | 0 | 1 | 7 | 1 | 3 | 4.23 |
| SP | Giolito, L.Giolito, Lucas # >> | 24 | 2019 | R | 71 | 15 | 15 | 2 | 6 | 7.65 | .395 | 1.93 | 12.2 | 5.2 | 9.4 | 62.1 | 84 | 53 | 53 | 18 | 36 | 65 | 0 | 0 | 0 | 0 | 3 | 2 | 2 | 6.52 |
| SU | Holland, G.Holland, Greg >> | 27 | 2013 | R | 75 | 37 | 0 | 3 | 2 | 2.66 | .232 | 0.87 | 5.0 | 2.9 | 10.0 | 47.1 | 26 | 16 | 14 | 5 | 15 | 52 | 0 | 2 | 7 | 0 | 0 | 2 | 1 | 3.26 |
| CL | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 81 | 29 | 0 | 0 | 0 | 0.70 | .218 | 0.83 | 5.0 | 2.6 | 8.8 | 38.1 | 21 | 4 | 3 | 0 | 11 | 37 | 0 | 10 | 1 | 0 | 0 | 0 | 0 | 1.92 |
| RP | Thornburg, T.Thornburg, Tyler >> | 27 | 2016 | R | 66 | 34 | 0 | 5 | 2 | 3.67 | .282 | 1.15 | 7.2 | 3.3 | 12.1 | 41.2 | 33 | 17 | 17 | 9 | 15 | 55 | 0 | 2 | 2 | 0 | 0 | 1 | 1 | 4.34 |
| RP | Santos, S.Santos, Sergio >> | 27 | 2011 | R | 33 | 8 | 0 | 0 | 1 | 5.23 | .367 | 1.65 | 7.2 | 8.1 | 14.4 | 10.1 | 8 | 6 | 6 | 1 | 9 | 16 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.10 |
| RP | Doolittle, S.Doolittle, Sean $ >> | 31 | 2018 | L | 99 | 38 | 0 | 2 | 5 | 6.00 | .347 | 1.52 | 9.9 | 3.9 | 10.5 | 42.0 | 46 | 29 | 28 | 9 | 18 | 49 | 0 | 3 | 3 | 0 | 0 | 3 | 0 | 4.95 |