| SP | Scherzer, M.Scherzer, Max $ >> | 33 | 2017 | R | 98 | 27 | 27 | 11 | 10 | 4.46 | .311 | 1.33 | 8.1 | 3.9 | 9.4 | 181.2 | 163 | 91 | 90 | 23 | 79 | 190 | 2 | 0 | 0 | 0 | 15 | 4 | 6 | 3.93 |
| SP | Beckett, J.Beckett, Josh >> | 31 | 2011 | R | 77 | 26 | 26 | 7 | 12 | 5.44 | .326 | 1.40 | 9.3 | 3.4 | 7.9 | 152.1 | 157 | 95 | 92 | 32 | 57 | 133 | 0 | 0 | 0 | 0 | 10 | 7 | 2 | 5.25 |
| SP | Giolito, L.Giolito, Lucas >> | 24 | 2019 | R | 72 | 26 | 26 | 8 | 10 | 5.22 | .350 | 1.60 | 10.5 | 3.9 | 10.3 | 150.0 | 175 | 88 | 87 | 23 | 65 | 171 | 0 | 0 | 0 | 0 | 11 | 2 | 4 | 4.05 |
| SP | Shields, J.Shields, James >> | 30 | 2011 | R | 63 | 27 | 25 | 10 | 11 | 6.08 | .353 | 1.62 | 10.5 | 4.1 | 6.9 | 158.1 | 184 | 108 | 107 | 37 | 72 | 122 | 4 | 0 | 0 | 0 | 7 | 3 | 3 | 5.92 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 76 | 0 | 3 | 6 | 4.93 | .301 | 1.29 | 8.6 | 3.0 | 10.4 | 95.0 | 91 | 52 | 52 | 15 | 32 | 110 | 0 | 9 | 3 | 0 | 0 | 0 | 2 | 3.75 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 87 | 70 | 0 | 6 | 3 | 3.68 | .296 | 1.23 | 7.2 | 3.9 | 10.6 | 85.2 | 68 | 35 | 35 | 10 | 37 | 100 | 0 | 10 | 6 | 0 | 0 | 3 | 3 | 3.59 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 56 | 0 | 2 | 2 | 3.92 | .285 | 1.15 | 7.7 | 2.7 | 12.1 | 64.1 | 55 | 28 | 28 | 5 | 19 | 86 | 0 | 10 | 3 | 0 | 0 | 3 | 7 | 2.36 |
| RP | McHugh, C.McHugh, Collin >> | 31 | 2018 | R | 64 | 40 | 0 | 4 | 2 | 4.36 | .265 | 1.04 | 7.8 | 1.7 | 10.5 | 53.2 | 46 | 26 | 26 | 9 | 10 | 62 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 3.55 |