| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 35 | 35 | 17 | 13 | 3.39 | .278 | 1.14 | 7.7 | 2.6 | 8.3 | 257.2 | 219 | 105 | 97 | 28 | 74 | 238 | 9 | 0 | 0 | 0 | 24 | 4 | 6 | 3.47 |
| SP | Arrieta, J.Arrieta, Jake † >> | 29 | 2015 | R | 97 | 35 | 35 | 20 | 9 | 3.54 | .288 | 1.19 | 8.2 | 2.6 | 7.5 | 236.1 | 214 | 104 | 93 | 35 | 68 | 196 | 3 | 0 | 0 | 1 | 25 | 5 | 2 | 4.19 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 93 | 34 | 34 | 10 | 14 | 4.79 | .320 | 1.41 | 8.7 | 4.0 | 8.2 | 218.0 | 210 | 130 | 116 | 40 | 97 | 199 | 2 | 0 | 0 | 0 | 18 | 1 | 5 | 4.91 |
| RP | Chapman, A.Chapman, Aroldis >> | 24 | 2012 | L | 96 | 83 | 0 | 1 | 4 | 3.93 | .297 | 1.24 | 6.0 | 5.3 | 10.2 | 68.2 | 45 | 34 | 30 | 16 | 40 | 77 | 0 | 1 | 4 | 0 | 0 | 2 | 2 | 5.65 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 29 | 2017 | R | 99 | 78 | 0 | 4 | 10 | 4.88 | .299 | 1.28 | 7.8 | 3.8 | 9.4 | 75.2 | 65 | 41 | 41 | 15 | 32 | 78 | 0 | 35 | 7 | 0 | 0 | 0 | 1 | 4.80 |
| RP | Wilhelm, H.Wilhelm, Hoyt # >> | 43 | 1965 | R | 81 | 58 | 0 | 3 | 3 | 3.97 | .311 | 1.35 | 8.7 | 3.5 | 5.8 | 90.2 | 87 | 50 | 40 | 12 | 35 | 58 | 0 | 4 | 0 | 0 | 0 | 1 | 4 | 4.64 |