| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 33 | 33 | 9 | 10 | 3.96 | .307 | 1.31 | 7.5 | 4.3 | 7.5 | 204.1 | 169 | 93 | 90 | 23 | 98 | 170 | 1 | 0 | 0 | 1 | 17 | 4 | 3 | 4.30 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 80 | 32 | 32 | 10 | 14 | 4.84 | .316 | 1.36 | 8.7 | 3.5 | 4.4 | 214.0 | 208 | 123 | 115 | 35 | 84 | 105 | 3 | 0 | 0 | 1 | 14 | 4 | 3 | 5.38 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 76 | 32 | 32 | 7 | 18 | 5.27 | .317 | 1.38 | 9.9 | 2.6 | 5.0 | 211.2 | 231 | 130 | 124 | 33 | 62 | 118 | 9 | 0 | 0 | 0 | 15 | 2 | 2 | 4.82 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 71 | 32 | 31 | 11 | 11 | 4.53 | .316 | 1.38 | 9.9 | 2.5 | 4.2 | 212.2 | 233 | 113 | 107 | 17 | 60 | 100 | 7 | 0 | 0 | 1 | 17 | 2 | 7 | 3.98 |
| CL | Benoit, J.Benoit, Joaquin † >> | 33 | 2010 | R | 95 | 67 | 0 | 4 | 10 | 5.14 | .303 | 1.29 | 9.4 | 2.3 | 8.9 | 68.1 | 71 | 40 | 39 | 8 | 17 | 67 | 0 | 33 | 8 | 0 | 0 | 1 | 2 | 3.35 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 93 | 69 | 0 | 2 | 3 | 2.87 | .286 | 1.20 | 6.3 | 4.6 | 9.5 | 53.1 | 37 | 17 | 17 | 1 | 27 | 56 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 2.66 |
| SU | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 64 | 0 | 0 | 2 | 2.86 | .269 | 1.08 | 6.0 | 3.8 | 8.1 | 72.1 | 48 | 26 | 23 | 7 | 30 | 65 | 0 | 4 | 2 | 0 | 0 | 2 | 1 | 3.79 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 62 | 0 | 4 | 2 | 3.10 | .265 | 1.03 | 6.0 | 3.2 | 8.4 | 61.0 | 41 | 25 | 21 | 3 | 22 | 57 | 0 | 1 | 3 | 0 | 0 | 3 | 2 | 3.00 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 42 | 0 | 5 | 4 | 5.19 | .326 | 1.41 | 9.0 | 3.8 | 7.7 | 43.1 | 43 | 25 | 25 | 6 | 18 | 37 | 0 | 1 | 0 | 0 | 0 | 2 | 3 | 4.49 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 34 | 0 | 0 | 3 | 6.54 | .349 | 1.61 | 10.5 | 4.4 | 7.3 | 31.2 | 36 | 24 | 23 | 6 | 15 | 25 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.35 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 34 | 0 | 3 | 1 | 4.27 | .265 | 1.06 | 7.6 | 2.0 | 9.0 | 46.1 | 39 | 23 | 22 | 4 | 10 | 46 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.85 |