| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 24 | 24 | 10 | 10 | 3.86 | .287 | 1.19 | 7.9 | 2.9 | 8.8 | 170.0 | 149 | 80 | 73 | 27 | 54 | 167 | 1 | 0 | 0 | 1 | 14 | 2 | 5 | 4.09 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 23 | 23 | 9 | 8 | 4.52 | .315 | 1.37 | 9.1 | 3.3 | 8.7 | 157.1 | 158 | 82 | 79 | 21 | 57 | 151 | 3 | 0 | 0 | 0 | 12 | 2 | 0 | 3.94 |
| SP | Pfiester, J.Pfiester, Jack # >> | 28 | 1906 | L | 74 | 22 | 22 | 10 | 8 | 4.24 | .298 | 1.26 | 8.6 | 2.8 | 4.4 | 170.0 | 162 | 82 | 80 | 17 | 53 | 84 | 11 | 0 | 0 | 0 | 9 | 2 | 1 | 4.28 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 48 | 0 | 6 | 2 | 2.35 | .288 | 1.17 | 7.6 | 3.1 | 8.8 | 53.2 | 45 | 14 | 14 | 2 | 18 | 52 | 0 | 6 | 1 | 0 | 0 | 2 | 0 | 2.66 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 25 | 0 | 2 | 2 | 4.06 | .285 | 1.19 | 7.8 | 2.9 | 9.3 | 31.0 | 27 | 14 | 14 | 6 | 10 | 32 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 4.42 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 13 | 0 | 2 | 0 | 7.90 | .379 | 1.83 | 13.2 | 4.2 | 7.6 | 13.2 | 19 | 12 | 12 | 2 | 6 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.69 |