| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 27 | 27 | 5 | 14 | 4.61 | .333 | 1.48 | 9.1 | 4.2 | 8.8 | 160.0 | 161 | 90 | 82 | 18 | 75 | 156 | 0 | 0 | 0 | 0 | 16 | 4 | 4 | 3.99 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 84 | 26 | 26 | 8 | 12 | 5.95 | .328 | 1.44 | 9.4 | 3.5 | 5.2 | 121.0 | 127 | 81 | 80 | 15 | 47 | 70 | 0 | 0 | 0 | 0 | 7 | 3 | 2 | 4.69 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 26 | 26 | 6 | 14 | 6.32 | .351 | 1.62 | 10.5 | 4.1 | 4.5 | 155.1 | 181 | 117 | 109 | 31 | 70 | 77 | 1 | 0 | 0 | 0 | 7 | 1 | 6 | 5.98 |
| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 68 | 25 | 25 | 8 | 16 | 5.90 | .351 | 1.59 | 11.2 | 3.2 | 7.3 | 158.2 | 196 | 114 | 104 | 29 | 57 | 129 | 2 | 0 | 0 | 1 | 7 | 4 | 3 | 4.91 |
| RP | Hader, J.Hader, Josh # >> | 24 | 2018 | L | 93 | 64 | 0 | 7 | 2 | 5.43 | .314 | 1.37 | 7.4 | 5.0 | 9.7 | 112.2 | 92 | 68 | 68 | 13 | 62 | 121 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 4.04 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 68 | 62 | 0 | 1 | 5 | 5.58 | .321 | 1.40 | 9.7 | 3.0 | 4.5 | 117.2 | 126 | 74 | 73 | 19 | 39 | 59 | 0 | 7 | 3 | 0 | 0 | 2 | 4 | 5.15 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 56 | 55 | 0 | 3 | 0 | 4.84 | .345 | 1.58 | 8.2 | 6.2 | 7.6 | 57.2 | 52 | 32 | 31 | 6 | 39 | 48 | 0 | 2 | 4 | 0 | 0 | 0 | 5 | 4.74 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 2 | 1 | 0 | 0 | 3.18 | .320 | 1.41 | 9.0 | 5.4 | 12.6 | 5.2 | 5 | 3 | 2 | 0 | 3 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.00 |
| SP | Raymond, B.Raymond, Bugs >> | 26 | 1908 | R | 41 | 7 | 0 | 0 | 0 | 12.34 | .470 | 2.66 | 19.6 | 5.7 | 7.4 | 11.2 | 24 | 16 | 16 | 2 | 7 | 9 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 5.64 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 49 | 44 | 0 | 2 | 6 | 6.55 | .363 | 1.71 | 11.1 | 4.4 | 9.0 | 78.1 | 96 | 59 | 57 | 15 | 38 | 78 | 0 | 3 | 0 | 0 | 0 | 0 | 3 | 4.96 |