| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 11 | 11 | 3 | 7 | 5.01 | .332 | 1.49 | 10.1 | 3.5 | 9.0 | 73.2 | 82 | 43 | 41 | 13 | 28 | 73 | 0 | 0 | 0 | 0 | 5 | 0 | 3 | 4.47 |
| SP | Maddux, G.Maddux, Greg # >> | 29 | 1995 | R | 89 | 11 | 11 | 6 | 4 | 3.03 | .297 | 1.25 | 8.9 | 2.5 | 5.0 | 77.1 | 76 | 28 | 26 | 6 | 21 | 43 | 1 | 0 | 0 | 0 | 8 | 1 | 2 | 3.75 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 11 | 11 | 7 | 2 | 2.81 | .287 | 1.18 | 6.2 | 4.6 | 7.0 | 73.2 | 50 | 26 | 23 | 4 | 37 | 57 | 0 | 0 | 0 | 0 | 8 | 2 | 1 | 3.75 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 21 | 0 | 1 | 2 | 1.33 | .228 | 0.89 | 6.3 | 1.8 | 7.2 | 20.1 | 14 | 3 | 3 | 2 | 4 | 16 | 0 | 16 | 0 | 0 | 0 | 0 | 0 | 3.30 |
| SU | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 24 | 0 | 1 | 0 | 2.63 | .301 | 1.29 | 6.8 | 4.9 | 8.6 | 24.0 | 18 | 7 | 7 | 2 | 13 | 23 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 3.79 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 24 | 0 | 1 | 0 | 5.11 | .383 | 1.86 | 13.5 | 3.8 | 7.5 | 12.1 | 18 | 7 | 7 | 2 | 5 | 10 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.75 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 20 | 0 | 2 | 1 | 4.76 | .311 | 1.35 | 7.9 | 4.2 | 8.5 | 17.0 | 15 | 10 | 9 | 2 | 8 | 16 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 4.06 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 8 | 0 | 0 | 0 | 1.35 | .231 | 0.90 | 7.5 | 1.5 | 7.5 | 6.2 | 5 | 1 | 1 | 1 | 1 | 5 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.00 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 14 | 0 | 0 | 0 | 4.97 | .356 | 1.66 | 12.8 | 3.0 | 8.3 | 12.2 | 17 | 7 | 7 | 3 | 4 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.42 |