| SP | Walsh, E.Walsh, Ed † $ >> | 29 | 1910 | R | 93 | 27 | 27 | 18 | 5 | 2.79 | .264 | 1.07 | 7.3 | 2.3 | 4.9 | 209.1 | 170 | 71 | 65 | 14 | 53 | 114 | 7 | 0 | 0 | 2 | 19 | 2 | 0 | 3.57 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 26 | 26 | 12 | 9 | 3.91 | .311 | 1.30 | 6.9 | 4.8 | 7.1 | 159.0 | 122 | 69 | 69 | 12 | 85 | 125 | 0 | 0 | 0 | 0 | 17 | 8 | 3 | 4.16 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 26 | 26 | 13 | 8 | 3.31 | .277 | 1.12 | 7.8 | 2.3 | 4.3 | 187.2 | 163 | 76 | 69 | 11 | 48 | 90 | 5 | 0 | 0 | 2 | 17 | 5 | 2 | 3.65 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 26 | 25 | 10 | 6 | 4.74 | .335 | 1.48 | 9.5 | 3.8 | 4.1 | 159.1 | 168 | 90 | 84 | 18 | 68 | 72 | 2 | 0 | 0 | 0 | 10 | 5 | 4 | 4.94 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 65 | 0 | 5 | 1 | 3.19 | .256 | 1.02 | 7.4 | 1.7 | 7.1 | 62.0 | 51 | 25 | 22 | 7 | 12 | 49 | 0 | 3 | 1 | 0 | 0 | 1 | 1 | 3.52 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 22 | 0 | 0 | 0 | 3.74 | .278 | 1.11 | 8.6 | 1.7 | 6.9 | 21.2 | 20 | 9 | 9 | 3 | 4 | 16 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 4.05 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 66 | 0 | 2 | 0 | 1.75 | .232 | 0.88 | 5.3 | 2.7 | 5.1 | 46.1 | 27 | 9 | 9 | 5 | 14 | 26 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 4.26 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 23 | 0 | 3 | 1 | 1.27 | .241 | 0.95 | 5.1 | 3.5 | 4.5 | 28.1 | 16 | 6 | 4 | 2 | 11 | 14 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 4.11 |
| CL | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 98 | 56 | 0 | 0 | 3 | 3.88 | .301 | 1.27 | 9.0 | 2.6 | 8.1 | 48.2 | 48 | 22 | 21 | 8 | 14 | 43 | 0 | 36 | 3 | 0 | 0 | 1 | 1 | 4.31 |