| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 11 | 11 | 5 | 3 | 3.00 | .297 | 1.25 | 8.0 | 3.2 | 4.8 | 75.0 | 67 | 26 | 25 | 10 | 27 | 40 | 2 | 0 | 0 | 0 | 9 | 1 | 1 | 4.79 |
| SP | Richard, J.Richard, J.R. $ >> | 30 | 1980 | R | 90 | 12 | 12 | 4 | 5 | 5.14 | .305 | 1.31 | 6.9 | 4.9 | 7.3 | 70.0 | 54 | 41 | 40 | 9 | 38 | 57 | 1 | 0 | 0 | 0 | 5 | 0 | 1 | 4.67 |
| SP | Johnson, R.Johnson, Randy # >> | 41 | 2004 | L | 84 | 11 | 11 | 3 | 3 | 5.61 | .296 | 1.25 | 9.3 | 1.9 | 8.9 | 61.0 | 63 | 40 | 38 | 12 | 13 | 60 | 0 | 0 | 0 | 0 | 4 | 1 | 1 | 4.28 |
| RP | Rivera, M.Rivera, Mariano $ >> | 39 | 2008 | R | 85 | 33 | 0 | 1 | 0 | 4.32 | .296 | 1.26 | 9.0 | 2.5 | 6.5 | 33.1 | 33 | 16 | 16 | 8 | 9 | 24 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.52 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 22 | 0 | 3 | 0 | 2.08 | .278 | 1.15 | 7.3 | 3.4 | 8.6 | 21.2 | 17 | 5 | 5 | 2 | 8 | 20 | 0 | 1 | 2 | 0 | 0 | 0 | 2 | 3.48 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 13 | 0 | 2 | 1 | 3.07 | .279 | 1.16 | 6.4 | 4.5 | 12.2 | 14.2 | 10 | 5 | 5 | 1 | 7 | 19 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.71 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 11 | 0 | 1 | 0 | 3.75 | .294 | 1.25 | 7.5 | 3.8 | 9.8 | 12.0 | 10 | 5 | 5 | 2 | 5 | 13 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 4.25 |
| CL | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 23 | 0 | 3 | 0 | 1.78 | .232 | 0.91 | 4.3 | 4.0 | 8.6 | 25.1 | 12 | 5 | 5 | 2 | 11 | 24 | 0 | 10 | 2 | 0 | 0 | 0 | 1 | 3.44 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 21 | 0 | 0 | 2 | 3.12 | .218 | 0.84 | 6.6 | 1.1 | 7.7 | 34.2 | 25 | 12 | 12 | 4 | 4 | 29 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 3.18 |