| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 26 | 26 | 8 | 13 | 4.28 | .298 | 1.25 | 8.6 | 2.7 | 8.3 | 174.2 | 166 | 89 | 83 | 33 | 52 | 160 | 1 | 0 | 0 | 0 | 16 | 4 | 6 | 4.59 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 27 | 27 | 12 | 8 | 3.76 | .293 | 1.23 | 8.1 | 3.0 | 7.0 | 179.1 | 161 | 78 | 75 | 28 | 59 | 139 | 1 | 0 | 0 | 0 | 16 | 3 | 4 | 4.52 |
| SP | Cueto, J.Cueto, Johnny # >> | 28 | 2014 | R | 75 | 26 | 26 | 10 | 12 | 4.71 | .320 | 1.39 | 9.5 | 3.1 | 6.4 | 177.2 | 186 | 96 | 93 | 20 | 61 | 126 | 3 | 0 | 0 | 1 | 11 | 4 | 4 | 4.15 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 95 | 70 | 0 | 6 | 1 | 4.14 | .313 | 1.32 | 7.0 | 4.9 | 9.2 | 87.0 | 68 | 40 | 40 | 8 | 47 | 89 | 0 | 3 | 2 | 0 | 0 | 4 | 1 | 3.91 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 64 | 0 | 4 | 6 | 3.27 | .310 | 1.34 | 7.7 | 4.3 | 7.9 | 77.0 | 66 | 30 | 28 | 7 | 37 | 68 | 0 | 10 | 2 | 0 | 0 | 1 | 0 | 3.90 |
| RP | Perkins, G.Perkins, Glen >> | 30 | 2013 | L | 49 | 30 | 0 | 0 | 1 | 4.22 | .267 | 1.09 | 8.7 | 1.1 | 8.7 | 32.0 | 31 | 15 | 15 | 4 | 4 | 31 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.06 |
| SP | McGinnity, J.McGinnity, Joe >> | 33 | 1904 | R | 50 | 2 | 2 | 0 | 0 | 4.80 | .286 | 1.20 | 7.2 | 3.6 | 3.6 | 15.0 | 12 | 9 | 8 | 2 | 6 | 6 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 5.13 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 57 | 12 | 0 | 4 | 0 | 3.71 | .363 | 1.71 | 8.5 | 6.9 | 4.2 | 17.0 | 16 | 7 | 7 | 2 | 13 | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 5.88 |