| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 31 | 31 | 14 | 10 | 2.79 | .276 | 1.13 | 8.1 | 2.2 | 7.1 | 242.1 | 217 | 87 | 75 | 21 | 58 | 192 | 8 | 0 | 0 | 1 | 24 | 2 | 6 | 3.29 |
| SP | Mathewson, C.Mathewson, Christy † $ >> | 28 | 1908 | R | 82 | 30 | 30 | 15 | 9 | 2.79 | .255 | 1.01 | 7.2 | 1.8 | 4.8 | 239.0 | 192 | 85 | 74 | 21 | 49 | 128 | 14 | 0 | 0 | 3 | 21 | 4 | 4 | 3.74 |
| SP | Ryan, N.Ryan, Nolan $$ >> | 44 | 1991 | R | 73 | 30 | 30 | 14 | 5 | 3.66 | .294 | 1.21 | 6.7 | 4.3 | 7.7 | 201.2 | 149 | 85 | 82 | 18 | 95 | 171 | 1 | 0 | 0 | 1 | 19 | 8 | 3 | 4.00 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 28 | 28 | 11 | 12 | 4.10 | .307 | 1.30 | 7.0 | 4.7 | 8.0 | 180.0 | 140 | 92 | 82 | 14 | 94 | 160 | 0 | 0 | 0 | 0 | 19 | 5 | 9 | 3.88 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 54 | 0 | 4 | 1 | 2.43 | .252 | 1.01 | 5.0 | 4.3 | 9.9 | 40.2 | 22 | 11 | 11 | 3 | 19 | 44 | 0 | 3 | 2 | 0 | 0 | 0 | 5 | 3.20 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 74 | 80 | 0 | 3 | 1 | 2.08 | .250 | 1.00 | 4.7 | 4.3 | 8.4 | 65.0 | 34 | 17 | 15 | 4 | 31 | 61 | 0 | 6 | 3 | 0 | 0 | 0 | 1 | 3.35 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 59 | 0 | 5 | 4 | 2.55 | .245 | 0.93 | 6.2 | 2.2 | 5.9 | 49.1 | 34 | 15 | 14 | 7 | 12 | 32 | 0 | 7 | 4 | 0 | 0 | 2 | 0 | 4.41 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 12 | 1 | 1 | 4 | 9.87 | .416 | 2.13 | 12.2 | 7.4 | 11.1 | 17.1 | 23 | 19 | 19 | 1 | 14 | 21 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 3.76 |