| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 95 | 29 | 29 | 7 | 19 | 4.05 | .308 | 1.29 | 8.7 | 3.0 | 8.3 | 204.1 | 197 | 98 | 92 | 23 | 67 | 189 | 2 | 0 | 0 | 0 | 15 | 9 | 2 | 3.73 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 71 | 29 | 29 | 5 | 11 | 5.28 | .341 | 1.54 | 10.2 | 3.8 | 7.2 | 163.2 | 184 | 101 | 96 | 23 | 68 | 130 | 0 | 0 | 0 | 0 | 9 | 2 | 6 | 4.53 |
| SP | Wilson, D.Wilson, Don # >> | 26 | 1971 | R | 59 | 28 | 28 | 9 | 15 | 6.21 | .345 | 1.55 | 10.1 | 3.8 | 6.9 | 168.0 | 189 | 118 | 116 | 28 | 71 | 128 | 1 | 0 | 0 | 0 | 10 | 5 | 5 | 5.00 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 59 | 28 | 28 | 7 | 11 | 4.84 | .343 | 1.54 | 10.7 | 3.2 | 5.5 | 182.1 | 216 | 106 | 98 | 24 | 64 | 111 | 5 | 0 | 0 | 0 | 13 | 5 | 2 | 4.63 |
| SP | Beckett, J.Beckett, Josh >> | 31 | 2011 | R | 56 | 27 | 27 | 7 | 14 | 6.57 | .360 | 1.68 | 11.0 | 4.1 | 6.2 | 148.0 | 181 | 112 | 108 | 29 | 67 | 102 | 0 | 0 | 0 | 0 | 9 | 2 | 5 | 5.57 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 96 | 75 | 0 | 1 | 5 | 4.33 | .290 | 1.20 | 8.1 | 2.8 | 10.7 | 99.2 | 89 | 49 | 48 | 11 | 31 | 118 | 0 | 4 | 2 | 0 | 0 | 2 | 2 | 3.06 |
| RP | Bautista, F.Bautista, Félix # >> | 28 | 2023 | R | 72 | 72 | 0 | 5 | 6 | 5.47 | .332 | 1.48 | 8.1 | 5.3 | 11.5 | 82.1 | 74 | 51 | 50 | 19 | 48 | 105 | 0 | 4 | 3 | 0 | 0 | 1 | 4 | 5.24 |
| SP | Perez, O.Perez, Odalis >> | 25 | 2002 | L | 51 | 4 | 0 | 1 | 0 | 0.00 | .357 | 1.67 | 6.0 | 9.0 | 3.0 | 3.0 | 2 | 0 | 0 | 0 | 3 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.33 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 55 | 29 | 0 | 5 | 4 | 7.61 | .392 | 1.89 | 12.7 | 4.6 | 10.7 | 49.2 | 69 | 43 | 42 | 13 | 25 | 58 | 0 | 1 | 1 | 0 | 0 | 2 | 3 | 5.73 |