| SP | Maddux, G.Maddux, Greg $ >> | 29 | 1995 | R | 90 | 18 | 18 | 9 | 6 | 3.52 | .272 | 1.11 | 8.3 | 1.7 | 7.3 | 135.1 | 124 | 58 | 53 | 16 | 26 | 110 | 7 | 0 | 0 | 3 | 10 | 2 | 2 | 3.53 |
| SP | Guidry, R.Guidry, Ron † # >> | 28 | 1978 | L | 81 | 17 | 17 | 10 | 4 | 2.90 | .270 | 1.11 | 6.9 | 3.1 | 7.0 | 133.1 | 102 | 46 | 43 | 9 | 46 | 103 | 5 | 0 | 0 | 3 | 12 | 0 | 4 | 3.37 |
| RP | Green, C.Green, Chad $ >> | 26 | 2017 | R | 95 | 38 | 0 | 3 | 5 | 3.50 | .286 | 1.18 | 6.9 | 3.8 | 9.4 | 61.2 | 47 | 24 | 24 | 7 | 26 | 64 | 0 | 4 | 1 | 0 | 0 | 1 | 3 | 3.72 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 72 | 11 | 0 | 0 | 1 | 2.19 | .288 | 1.22 | 4.5 | 6.8 | 7.5 | 12.1 | 6 | 3 | 3 | 1 | 9 | 10 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 4.67 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 65 | 15 | 0 | 0 | 0 | 0.45 | .231 | 0.90 | 4.1 | 4.1 | 6.3 | 20.0 | 9 | 1 | 1 | 1 | 9 | 14 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.60 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 66 | 11 | 2 | 0 | 2 | 6.91 | .351 | 1.59 | 10.1 | 4.2 | 8.5 | 56.0 | 63 | 43 | 43 | 12 | 26 | 53 | 1 | 0 | 0 | 0 | 1 | 2 | 1 | 5.39 |