| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 28 | 28 | 9 | 11 | 3.80 | .302 | 1.28 | 7.8 | 3.7 | 9.8 | 184.2 | 160 | 82 | 78 | 25 | 76 | 201 | 1 | 0 | 0 | 1 | 17 | 4 | 3 | 3.89 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 66 | 26 | 26 | 9 | 13 | 5.64 | .325 | 1.43 | 9.8 | 3.1 | 9.4 | 158.0 | 172 | 102 | 99 | 31 | 54 | 165 | 5 | 0 | 0 | 1 | 11 | 2 | 5 | 4.53 |
| SP | Hamels, C.Hamels, Cole # >> | 28 | 2011 | L | 62 | 26 | 26 | 8 | 9 | 4.54 | .295 | 1.24 | 9.2 | 2.0 | 7.3 | 174.1 | 177 | 94 | 88 | 37 | 39 | 141 | 4 | 0 | 0 | 0 | 16 | 3 | 2 | 4.87 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 74 | 0 | 5 | 3 | 2.33 | .257 | 1.03 | 5.9 | 3.4 | 10.0 | 100.1 | 65 | 26 | 26 | 9 | 38 | 111 | 0 | 7 | 2 | 0 | 0 | 1 | 0 | 3.12 |
| RP | Hochevar, L.Hochevar, Luke # >> | 30 | 2013 | R | 74 | 62 | 0 | 1 | 5 | 5.33 | .330 | 1.43 | 10.1 | 2.9 | 7.7 | 77.2 | 86 | 49 | 46 | 16 | 25 | 66 | 0 | 10 | 1 | 0 | 0 | 4 | 6 | 5.12 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 60 | 41 | 0 | 1 | 4 | 4.53 | .326 | 1.43 | 7.0 | 6.1 | 9.9 | 49.2 | 38 | 27 | 25 | 8 | 33 | 54 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 5.00 |
| SP | Beckett, J.Beckett, Josh >> | 31 | 2011 | R | 58 | 26 | 7 | 5 | 3 | 5.35 | .340 | 1.53 | 10.2 | 3.7 | 7.2 | 70.2 | 79 | 43 | 42 | 15 | 29 | 56 | 0 | 1 | 0 | 0 | 3 | 1 | 2 | 5.47 |