| SP | Greinke, Z.Greinke, Zack $ >> | 32 | 2015 | R | 94 | 19 | 19 | 9 | 5 | 3.00 | .273 | 1.13 | 7.9 | 2.2 | 6.4 | 144.0 | 127 | 52 | 48 | 12 | 35 | 103 | 3 | 0 | 0 | 0 | 13 | 0 | 0 | 3.38 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 91 | 19 | 19 | 10 | 4 | 3.77 | .291 | 1.22 | 8.0 | 3.0 | 8.6 | 126.2 | 112 | 55 | 53 | 25 | 42 | 120 | 1 | 0 | 0 | 0 | 13 | 2 | 1 | 4.72 |
| SP | Fernandez, S.Fernandez, Sid † >> | 23 | 1985 | L | 53 | 17 | 17 | 9 | 4 | 1.68 | .222 | 0.84 | 4.5 | 3.1 | 8.1 | 134.0 | 67 | 25 | 25 | 8 | 46 | 121 | 2 | 0 | 0 | 1 | 15 | 2 | 0 | 3.04 |
| SP | Perry, G.Perry, Gaylord # >> | 34 | 1972 | R | 67 | 17 | 16 | 9 | 5 | 3.63 | .266 | 1.08 | 7.8 | 2.0 | 5.1 | 124.0 | 107 | 51 | 50 | 17 | 27 | 70 | 8 | 0 | 0 | 3 | 7 | 1 | 1 | 4.33 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 46 | 0 | 1 | 1 | 2.52 | .284 | 1.19 | 7.6 | 3.2 | 9.5 | 53.2 | 45 | 17 | 15 | 5 | 19 | 56 | 0 | 8 | 2 | 0 | 0 | 0 | 4 | 3.19 |
| RP | Chapman, A.Chapman, Aroldis † >> | 26 | 2014 | L | 92 | 33 | 0 | 5 | 2 | 2.67 | .294 | 1.13 | 5.2 | 5.2 | 10.6 | 33.2 | 19 | 10 | 10 | 2 | 19 | 39 | 0 | 7 | 1 | 0 | 0 | 4 | 0 | 3.52 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 9 | 0 | 1 | 1 | 3.27 | .283 | 1.09 | 4.9 | 4.9 | 5.7 | 11.0 | 6 | 4 | 4 | 2 | 6 | 7 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.00 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 73 | 7 | 0 | 1 | 1 | 5.96 | .313 | 1.37 | 10.6 | 2.0 | 7.0 | 22.2 | 26 | 22 | 15 | 6 | 5 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.68 |