| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 28 | 28 | 14 | 8 | 2.73 | .248 | 0.97 | 6.4 | 2.4 | 9.4 | 194.1 | 137 | 60 | 59 | 20 | 52 | 203 | 1 | 0 | 0 | 1 | 22 | 3 | 0 | 3.10 |
| SP | Hudson, D.Hudson, Daniel # >> | 23 | 2010 | R | 72 | 27 | 27 | 5 | 12 | 4.96 | .331 | 1.47 | 9.5 | 3.8 | 6.3 | 158.0 | 167 | 88 | 87 | 20 | 66 | 110 | 1 | 0 | 0 | 0 | 13 | 2 | 3 | 4.54 |
| SP | Strasburg, S.Strasburg, Stephen # >> | 28 | 2017 | R | 65 | 27 | 27 | 7 | 16 | 6.09 | .345 | 1.57 | 10.1 | 4.1 | 9.4 | 164.0 | 184 | 115 | 111 | 41 | 74 | 172 | 1 | 0 | 0 | 0 | 7 | 1 | 2 | 5.52 |
| SP | Smoltz, J.Smoltz, John >> | 29 | 1996 | R | 62 | 23 | 23 | 3 | 15 | 6.45 | .350 | 1.60 | 11.6 | 2.9 | 9.7 | 148.0 | 190 | 108 | 106 | 30 | 47 | 159 | 3 | 0 | 0 | 0 | 8 | 2 | 2 | 4.48 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 73 | 0 | 2 | 7 | 3.41 | .303 | 1.25 | 7.7 | 3.6 | 9.4 | 118.2 | 101 | 47 | 45 | 16 | 47 | 123 | 0 | 6 | 4 | 0 | 0 | 7 | 0 | 4.05 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 82 | 63 | 0 | 4 | 2 | 2.96 | .307 | 1.29 | 7.4 | 4.2 | 6.1 | 85.0 | 70 | 32 | 28 | 8 | 40 | 58 | 0 | 10 | 3 | 0 | 0 | 3 | 0 | 4.38 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 64 | 42 | 0 | 3 | 2 | 3.72 | .256 | 1.03 | 5.6 | 3.8 | 10.3 | 48.1 | 30 | 20 | 20 | 3 | 20 | 55 | 0 | 5 | 1 | 0 | 0 | 0 | 4 | 2.77 |
| RP | Benitez, A.Benitez, Armando >> | 27 | 1999 | R | 57 | 29 | 0 | 2 | 1 | 4.99 | .366 | 1.73 | 9.3 | 6.6 | 13.2 | 30.2 | 31 | 17 | 17 | 6 | 22 | 44 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 4.87 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 52 | 30 | 0 | 1 | 2 | 4.14 | .306 | 1.30 | 7.8 | 3.9 | 8.8 | 37.0 | 32 | 17 | 17 | 4 | 16 | 36 | 0 | 2 | 0 | 0 | 0 | 1 | 4 | 3.84 |