| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 97 | 30 | 30 | 9 | 13 | 3.69 | .290 | 1.20 | 7.7 | 3.1 | 8.6 | 210.0 | 180 | 89 | 86 | 30 | 72 | 201 | 3 | 0 | 0 | 1 | 21 | 5 | 3 | 4.04 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 84 | 29 | 29 | 7 | 16 | 4.73 | .337 | 1.48 | 10.1 | 3.2 | 5.6 | 192.0 | 216 | 121 | 101 | 29 | 68 | 119 | 5 | 0 | 0 | 2 | 14 | 9 | 1 | 4.93 |
| SP | Valenzuela, F.Valenzuela, Fernando >> | 21 | 1981 | L | 60 | 27 | 27 | 11 | 11 | 5.04 | .344 | 1.54 | 9.1 | 4.7 | 6.9 | 182.0 | 185 | 104 | 102 | 29 | 95 | 139 | 2 | 0 | 0 | 0 | 11 | 6 | 2 | 5.21 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 73 | 0 | 2 | 2 | 3.60 | .266 | 1.04 | 7.9 | 1.5 | 9.9 | 105.0 | 92 | 43 | 42 | 15 | 17 | 116 | 0 | 5 | 6 | 0 | 0 | 5 | 2 | 3.28 |
| RP | Boxberger, B.Boxberger, Brad # >> | 26 | 2014 | R | 81 | 63 | 0 | 5 | 6 | 5.56 | .347 | 1.59 | 10.0 | 4.4 | 11.2 | 69.2 | 77 | 44 | 43 | 10 | 34 | 86 | 0 | 5 | 4 | 0 | 0 | 0 | 4 | 3.87 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 42 | 0 | 4 | 5 | 6.65 | .380 | 1.82 | 10.0 | 6.5 | 9.2 | 47.1 | 52 | 37 | 35 | 10 | 34 | 48 | 0 | 5 | 4 | 0 | 0 | 1 | 2 | 5.96 |
| RP | Benitez, A.Benitez, Armando >> | 27 | 1999 | R | 56 | 38 | 0 | 3 | 0 | 3.89 | .331 | 1.46 | 6.8 | 6.3 | 11.9 | 37.0 | 28 | 16 | 16 | 2 | 26 | 49 | 0 | 4 | 1 | 0 | 0 | 1 | 1 | 3.24 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 49 | 39 | 0 | 0 | 3 | 6.00 | .308 | 1.31 | 8.6 | 3.2 | 10.4 | 45.0 | 43 | 33 | 30 | 9 | 16 | 52 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 4.42 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 57 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Weaver, J.Weaver, Jered >> | 29 | 2011 | R | 52 | 18 | 0 | 2 | 1 | 4.74 | .305 | 1.26 | 8.5 | 2.8 | 9.0 | 19.0 | 18 | 10 | 10 | 3 | 6 | 19 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 4.16 |