| SP | Tiant, L.Tiant, Luis $ >> | 28 | 1968 | R | 97 | 25 | 25 | 9 | 8 | 3.51 | .295 | 1.22 | 7.7 | 3.3 | 8.4 | 182.0 | 155 | 72 | 71 | 13 | 67 | 170 | 6 | 0 | 0 | 1 | 16 | 6 | 1 | 3.26 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 24 | 24 | 14 | 9 | 4.65 | .329 | 1.42 | 9.5 | 3.3 | 8.3 | 151.0 | 160 | 83 | 78 | 27 | 55 | 139 | 0 | 0 | 0 | 0 | 12 | 7 | 2 | 4.72 |
| SP | Mathewson, C.Mathewson, Christy # >> | 28 | 1908 | R | 83 | 24 | 24 | 12 | 7 | 3.46 | .261 | 1.04 | 7.9 | 1.5 | 5.0 | 179.1 | 158 | 71 | 69 | 25 | 29 | 100 | 6 | 0 | 0 | 1 | 15 | 3 | 1 | 4.23 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 24 | 24 | 12 | 10 | 5.34 | .311 | 1.32 | 9.4 | 2.5 | 5.1 | 150.0 | 157 | 93 | 89 | 20 | 41 | 85 | 4 | 0 | 0 | 0 | 10 | 5 | 4 | 4.52 |
| CL | Jansen, K.Jansen, Kenley † $$ >> | 28 | 2016 | R | 97 | 55 | 0 | 1 | 9 | 3.90 | .305 | 1.30 | 9.2 | 2.6 | 9.2 | 55.1 | 56 | 24 | 24 | 2 | 16 | 56 | 0 | 35 | 2 | 0 | 0 | 1 | 0 | 2.36 |
| SU | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 61 | 0 | 2 | 3 | 2.66 | .275 | 1.11 | 6.9 | 3.2 | 7.3 | 67.2 | 51 | 20 | 20 | 6 | 24 | 54 | 0 | 3 | 2 | 0 | 0 | 2 | 0 | 3.72 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 43 | 0 | 0 | 1 | 2.91 | .261 | 1.04 | 5.5 | 3.9 | 6.3 | 46.1 | 28 | 16 | 15 | 4 | 20 | 32 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 4.11 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 81 | 33 | 0 | 3 | 1 | 2.70 | .310 | 1.35 | 7.4 | 4.7 | 7.9 | 40.0 | 33 | 12 | 12 | 1 | 21 | 35 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.15 |